Mouse Anti-RABL6 Recombinant Antibody (CBXC-0687) (CBMAB-C5419-CQ)

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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal
Mouse
Clone
CBXC-0687
Application
IF, S-ELISA, ELISA, WB
Immunogen
C9orf86 (AAH02945, 1 a.a.-477 a.a) Full length recombinant protein with GST tag.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
RAB, Member RAS Oncogene Family Like 6
Introduction
This gene encodes a member of the Ras superfamily of small GTPases. The encoded protein binds to both GTP and GDP and may play a role in cell growth and survival. Overexpression of this gene may play a role in breast cancer tumorigenesis, and pseudogenes of this gene are located on the long arm of chromosome 2 and the short arm of chromosome 18. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Entrez Gene ID
UniProt ID
Alternative Names
RAB, Member RAS Oncogene Family Like 6; Partner Of ARF; Rab-Like Protein 1; C9orf86; RBEL1; PARF; Chromosome 9 Open Reading Frame 86;
Function
May enhance cellular proliferation. May reduce growth inhibitory activity of CDKN2A.
Cellular Location
Isoform 1
Cytoplasm
Predominantly cytoplasmic (PubMed:17962191).
Isoform 3
Nucleus
Predominantly nuclear (PubMed:17962191).
PTM
Isoform 1 is O-glycosylated, while other isoforms are not.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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