RASSF8
This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
Full Name
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
Biological Process
Signal transduction
Involvement in disease
A chromosomal aberration involving RASSF8 is found in a complex type of synpolydactyly referred to as 3/3-prime/4 synpolydactyly associated with metacarpal and metatarsal synostoses. Reciprocal translocation t(12;22)(p11.2;q13.3) with FBLN1.
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Anti-RASSF8 antibodies
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Target: RASSF8
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBCNR-258
Application*: WB, P
Target: RASSF8
Host: Mouse
Antibody Isotype: IgG1
Specificity: Mouse, Rat, Dog, Human, Monkey
Clone: 3F7
Application*: WB, P, IF
Target: RASSF8
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: 2G1
Application*: E, IF, IH, IP, WB
Target: RASSF8
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2F9
Application*: WB, IF
Target: RASSF8
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2B6
Application*: WB, IH
Target: RASSF8
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1F5
Application*: WB, IH
Target: RASSF8
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1F12
Application*: WB, IF
Target: RASSF8
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1A1
Application*: WB, IH
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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