RASSF8

This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
Full Name
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
Biological Process
Signal transduction
Involvement in disease
A chromosomal aberration involving RASSF8 is found in a complex type of synpolydactyly referred to as 3/3-prime/4 synpolydactyly associated with metacarpal and metatarsal synostoses. Reciprocal translocation t(12;22)(p11.2;q13.3) with FBLN1.
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Anti-RASSF8 antibodies

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Target: RASSF8
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBCNR-258
Application*: WB, P
Target: RASSF8
Host: Mouse
Antibody Isotype: IgG1
Specificity: Mouse, Rat, Dog, Human, Monkey
Clone: 3F7
Application*: WB, P, IF
Target: RASSF8
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: 2G1
Application*: E, IF, IH, IP, WB
Target: RASSF8
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2F9
Application*: WB, IF
Target: RASSF8
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2B6
Application*: WB, IH
Target: RASSF8
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1F5
Application*: WB, IH
Target: RASSF8
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1F12
Application*: WB, IF
Target: RASSF8
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1A1
Application*: WB, IH
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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