RERG

RERG, a member of the RAS superfamily of GTPases, inhibits cell proliferation and tumor formation (Finlin et al., 2001 [PubMed 11533059]).[supplied by OMIM

RAS-like, estrogen-regulated, growth inhibitor

Binds GDP/GTP and possesses intrinsic GTPase activity. Has higher affinity for GDP than for GTP. In cell lines overexpression leads to a reduction in the rate of proliferation, colony formation and in tumorigenic potential.

Biological Process negative regulation of cell growthManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of cell population proliferationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process Ras protein signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process response to hormoneManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process small GTPase mediated signal transduction1 PublicationNAS:UniProtKB

Cytoplasm