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Mouse Anti-RERG Recombinant Antibody (1C5) (CBMAB-R2200-CN)

This product is a Mouse antibody that recognizes RERG. The antibody 1C5 can be used for immunoassay techniques such as: ELISA, WB.
See all RERG antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1C5
Antibody Isotype
IgG2b, κ
Application
ELISA, WB

Basic Information

Immunogen
Full length recombinant corresponding to aa. 1-200 from human RERG (H07997) with GST tag
Specificity
Human
Antibody Isotype
IgG2b, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2

Target

Full Name
RAS-like, estrogen-regulated, growth inhibitor
Introduction
RERG, a member of the RAS superfamily of GTPases, inhibits cell proliferation and tumor formation (Finlin et al., 2001 [PubMed 11533059]). [supplied by OMIM, Mar 2009]
Entrez Gene ID
85004
UniProt ID
Q96A58
Alternative Names
RAS Like Estrogen Regulated Growth Inhibitor; RAS-Like, Estrogen-Regulated, Growth Inhibitor;
Function
Binds GDP/GTP and possesses intrinsic GTPase activity. Has higher affinity for GDP than for GTP. In cell lines overexpression leads to a reduction in the rate of proliferation, colony formation and in tumorigenic potential.
Biological Process
Biological Process negative regulation of cell growthManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of cell population proliferationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process Ras protein signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process response to hormoneManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process small GTPase mediated signal transduction1 PublicationNAS:UniProtKB
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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