Mouse Anti-RERG Recombinant Antibody (CBCNR-410) (CBMAB-R2201-CN)

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Basic Information

Host Animal
Mouse
Clone
CBCNR-410
Application
IF, ELISA, WB
Immunogen
RERG (H07997, aa. 1-199) full-length recombinant protein with GST tag
Specificity
Human
Antibody Isotype
IgG2b, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
1× PBS, pH 7.2
More Infomation

Target

Full Name
RAS-like, estrogen-regulated, growth inhibitor
Introduction
RERG, a member of the RAS superfamily of GTPases, inhibits cell proliferation and tumor formation (Finlin et al., 2001 [PubMed 11533059]). [supplied by OMIM, Mar 2009]
Entrez Gene ID
UniProt ID
Alternative Names
RAS Like Estrogen Regulated Growth Inhibitor; RAS-Like, Estrogen-Regulated, Growth Inhibitor;
Function
Binds GDP/GTP and possesses intrinsic GTPase activity. Has higher affinity for GDP than for GTP. In cell lines overexpression leads to a reduction in the rate of proliferation, colony formation and in tumorigenic potential.
Biological Process
Biological Process negative regulation of cell growthManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of cell population proliferationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process Ras protein signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process response to hormoneManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process small GTPase mediated signal transduction1 PublicationNAS:UniProtKB
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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