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RNF181

RNF181 binds the integrin alpha-IIb (ITGA2B; MIM 607759)/beta-3 (ITGB3; MIM 173470) complex and has E3 ubiquitin ligase activity (Brophy et al., 2008 [PubMed 18331836]).[supplied by OMIM, Dec 2008]

Full Name

Ring Finger Protein 181

Function

E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates (PubMed:18331836).
Catalyzes monoubiquitination of 26S proteasome subunit PSMC2/RPT1 (PubMed:24811749).

Biological Process

Biological Process protein autoubiquitinationManual Assertion Based On ExperimentIDA:FlyBase
Biological Process protein ubiquitinationManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Cytoplasm

PTM

Autoubiquitinated as part of the enzymatic reaction.

Anti-RNF181 antibodies

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Mouse Anti-RNF181 Recombinant Antibody (CBYJL-2334) (CBMAB-L2636-YJ)

SDS

Target: RNF181

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBYJL-2334

Application*: WB

RNF181 Matched Antibody Pair (1010) (APMAB-1010LY)

SDS

Target: RNF181

Specificity: Human

RNF181 Matched Antibody Pair (1009) (APMAB-1009LY)

SDS

Target: RNF181

Specificity: Human

Mouse Anti-RNF181 Recombinant Antibody (F-2) (CBMAB-R2971-CN)

SDS

Target: RNF181

Host: Mouse

Specificity: Human

Clone: F-2

Application*: WB, IP, IF, P, E

Mouse Anti-RNF181 Recombinant Antibody (5A7) (CBMAB-R2970-CN)

SDS

Target: RNF181

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 5A7

Application*: E, WB

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)

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