RNF25

The protein encoded by this gene contains a RING finger motif. The mouse counterpart of this protein has been shown to interact with Rela, the p65 subunit of NF-kappaB (NFKB), and modulate NFKB-mediated transcription activity. The mouse protein also binds ubiquitin-conjugating enzymes (E2s) and is a substrate for E2-dependent ubiquitination. [provided by RefSeq]

Full Name

ring finger protein 25

Function

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NKD2 (By similarity).
Stimulates transcription mediated by NF-kappa-B.

Biological Process

Biological Process positive regulation of NF-kappaB transcription factor activityManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process protein ubiquitinationISS:UniProtKB

Cellular Location

cytosol
nucleus

PTM

Ubiquitinated.

Anti-RNF25 antibodies

Mouse Anti-RNF25 Recombinant Antibody (E-10) (CBMAB-R3026-CN)

Datasheet

SDS

Target: RNF25

Host: Mouse

Specificity: Mouse, Rat, Human

Clone: E-10

Application*: WB, IP, IF, E

Mouse Anti-RNF25 Recombinant Antibody (CBCNR-616) (CBMAB-R3025-CN)

Datasheet

SDS

Target: RNF25

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBCNR-616

Application*: WB, P

Mouse Anti-RNF25 Recombinant Antibody (CBCNR-615) (CBMAB-R3024-CN)

Datasheet

SDS

Target: RNF25

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBCNR-615

Application*: P, E, WB

Mouse Anti-RNF25 Recombinant Antibody (C-12) (CBMAB-R3023-CN)

Datasheet

SDS

Target: RNF25

Host: Mouse

Specificity: Human

Clone: C-12

Application*: WB, IP, IF, E

Mouse Anti-RNF25 Recombinant Antibody (1D10) (CBMAB-R3022-CN)

Datasheet

SDS

Target: RNF25

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 1D10

Application*: E, IH, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)