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Mouse Anti-RNF25 Recombinant Antibody (E-10) (CBMAB-R3026-CN)


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Summary

Host Animal
Mouse
Specificity
Mouse, Rat, Human
Clone
E-10
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Mouse, Rat, Human
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Target

Full Name
ring finger protein 25
Introduction
The protein encoded by this gene contains a RING finger motif. The mouse counterpart of this protein has been shown to interact with Rela, the p65 subunit of NF-kappaB (NFKB), and modulate NFKB-mediated transcription activity. The mouse protein also binds ubiquitin-conjugating enzymes (E2s) and is a substrate for E2-dependent ubiquitination. [provided by RefSeq, Jul 2008]
Entrez Gene ID
Human64320
Mouse57751
Rat301515
UniProt ID
HumanQ96BH1
MouseQ9QZR0
RatD3ZQ26
Alternative Names
Ring Finger Protein 25; RING-Type E3 Ubiquitin Transferase RNF25; RING Finger Protein 25; E3 Ubiquitin-Protein Ligase RNF25; Ring Finger Protein AO7; EC 2.3.2.27; AO7;
Function
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NKD2 (By similarity).
Stimulates transcription mediated by NF-kappa-B.
Biological Process
Biological Process positive regulation of NF-kappaB transcription factor activityManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process protein ubiquitinationISS:UniProtKB
Cellular Location
cytosol
nucleus
PTM
Ubiquitinated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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