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Mouse Anti-RNF25 Recombinant Antibody (1D10) (CBMAB-R3022-CN)

This product is a Mouse antibody that recognizes RNF25. The antibody 1D10 can be used for immunoassay techniques such as: ELISA, IHC, WB.
See all RNF25 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1D10
Antibody Isotype
IgG1, κ
Application
ELISA, IHC, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa. 352-460 from human RNF25 (NP_071898) with GST tag
Specificity
Human
Antibody Isotype
IgG1, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2

Target

Full Name
ring finger protein 25
Introduction
The protein encoded by this gene contains a RING finger motif. The mouse counterpart of this protein has been shown to interact with Rela, the p65 subunit of NF-kappaB (NFKB), and modulate NFKB-mediated transcription activity. The mouse protein also binds ubiquitin-conjugating enzymes (E2s) and is a substrate for E2-dependent ubiquitination. [provided by RefSeq, Jul 2008]
Entrez Gene ID
64320
UniProt ID
Q96BH1
Alternative Names
Ring Finger Protein 25; RING-Type E3 Ubiquitin Transferase RNF25; RING Finger Protein 25; E3 Ubiquitin-Protein Ligase RNF25; Ring Finger Protein AO7; EC 2.3.2.27; AO7;
Function
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NKD2 (By similarity).
Stimulates transcription mediated by NF-kappa-B.
Biological Process
Biological Process positive regulation of NF-kappaB transcription factor activityManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process protein ubiquitinationISS:UniProtKB
Cellular Location
cytosol
nucleus
PTM
Ubiquitinated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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