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RNMT

RNMT (RNA Guanine-7 Methyltransferase) is a Protein Coding gene. Among its related pathways are mRNA Splicing - Major Pathway and Gene Expression. Gene Ontology (GO) annotations related to this gene include RNA binding and mRNA (guanine-N7-)-methyltransferase activity.

Full Name

RNA (guanine-7-) methyltransferase

Function

Catalytic subunit of the mRNA-capping methyltransferase RNMT:RAMAC complex that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs (PubMed:9790902, PubMed:9705270, PubMed:10347220, PubMed:11114884, PubMed:22099306, PubMed:27422871).
Binds RNA containing 5'-terminal GpppC (PubMed:11114884).

Biological Process

Biological Process 7-methylguanosine mRNA cappingManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process cellular response to leukemia inhibitory factorIEA:Ensembl

Cellular Location

Nucleus

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Anti-RNMT antibodies

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Rabbit Anti-RNMT (AA 1-932) Recombinant Antibody (CBFYM-3093) (CBMAB-M3289-FY)

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Target: RNMT

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: CBFYM-3093

Application*: E

Mouse Anti-RNMT Recombinant Antibody (CBFYH-3655) (CBMAB-H4216-FY)

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Target: RNMT

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYH-3655

Application*: WB, P

Rabbit Anti-RNMT Recombinant Antibody (NL8) (CBMAB-R3074-CN)

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Target: RNMT

Host: Rabbit

Specificity: Human

Clone: NL8

Application*: WB

Mouse Anti-RNMT Recombinant Antibody (3H3-1D12) (CBMAB-R3073-CN)

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Target: RNMT

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 3H3-1D12

Application*: E, IF, IH, WB

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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