RNMT
RNMT (RNA Guanine-7 Methyltransferase) is a Protein Coding gene. Among its related pathways are mRNA Splicing - Major Pathway and Gene Expression. Gene Ontology (GO) annotations related to this gene include RNA binding and mRNA (guanine-N7-)-methyltransferase activity.
Full Name
RNA (guanine-7-) methyltransferase
Function
Catalytic subunit of the mRNA-capping methyltransferase RNMT:RAMAC complex that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs (PubMed:9790902, PubMed:9705270, PubMed:10347220, PubMed:11114884, PubMed:22099306, PubMed:27422871).
Binds RNA containing 5'-terminal GpppC (PubMed:11114884).
Binds RNA containing 5'-terminal GpppC (PubMed:11114884).
Biological Process
Biological Process 7-methylguanosine mRNA cappingManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process cellular response to leukemia inhibitory factorIEA:Ensembl
Biological Process cellular response to leukemia inhibitory factorIEA:Ensembl
Cellular Location
Nucleus
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Anti-RNMT antibodies
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Target: RNMT
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYM-3093
Application*: E
Target: RNMT
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-3655
Application*: WB, P
Target: RNMT
Host: Rabbit
Specificity: Human
Clone: NL8
Application*: WB
Target: RNMT
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3H3-1D12
Application*: E, IF, IH, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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