Rabbit Anti-RNMT Recombinant Antibody (NL8) (CBMAB-R3074-CN)

Name: Rabbit Anti-RNMT Recombinant Antibody (NL8)
SKU: CBMAB-R3074-CN
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Rabbit

Clone

NL8

Application

Immunogen

KLH-conjugated, synthetic peptide in which pYpY corresponds to phosphorylated aa. 1234-1234 of human Met/HGFR

Specificity

Human

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

Tissue culture supernatant

More Infomation

Target

Full Name

RNA (guanine-7-) methyltransferase

Introduction

RNMT (RNA Guanine-7 Methyltransferase) is a Protein Coding gene. Among its related pathways are mRNA Splicing - Major Pathway and Gene Expression. Gene Ontology (GO) annotations related to this gene include RNA binding and mRNA (guanine-N7-)-methyltransferase activity.

Entrez Gene ID

8731

UniProt ID

O43148

Alternative Names

RNA Guanine-7 Methyltransferase; MRNA (Guanine-N(7)-)-Methyltransferase; MRNA Cap Guanine-N7 Methyltransferase; RNA (Guanine-7-) Methyltransferase; MRNA Cap Methyltransferase; EC 2.1.1.56; RG7MT1; HCMT1; Hcm1p;

Function

Catalytic subunit of the mRNA-capping methyltransferase RNMT:RAMAC complex that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs (PubMed:9790902, PubMed:9705270, PubMed:10347220, PubMed:11114884, PubMed:22099306, PubMed:27422871).
Binds RNA containing 5'-terminal GpppC (PubMed:11114884).

Biological Process

Biological Process 7-methylguanosine mRNA cappingManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process cellular response to leukemia inhibitory factorIEA:Ensembl

Cellular Location

Nucleus

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Mouse Anti-RNMT Recombinant Antibody (3H3-1D12) (CAT#: CBMAB-R3073-CN)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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