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Mouse Anti-RNMT Recombinant Antibody (3H3-1D12) (CBMAB-R3073-CN)

This product is a Mouse antibody that recognizes RNMT. The antibody 3H3-1D12 can be used for immunoassay techniques such as: ELISA, IF, IHC, WB.
See all RNMT antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
3H3-1D12
Antibody Isotype
IgG1, κ
Application
ELISA, IF, IHC, WB

Basic Information

Immunogen
Full length recombinant corresponding to aa. 1-476 from RNMT (H36798) with GST tag
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2

Target

Full Name
RNA (guanine-7-) methyltransferase
Introduction
RNMT (RNA Guanine-7 Methyltransferase) is a Protein Coding gene. Among its related pathways are mRNA Splicing - Major Pathway and Gene Expression. Gene Ontology (GO) annotations related to this gene include RNA binding and mRNA (guanine-N7-)-methyltransferase activity.
Entrez Gene ID
8731
UniProt ID
O43148
Alternative Names
RNA Guanine-7 Methyltransferase; MRNA (Guanine-N(7)-)-Methyltransferase; MRNA Cap Guanine-N7 Methyltransferase; RNA (Guanine-7-) Methyltransferase; MRNA Cap Methyltransferase; EC 2.1.1.56; RG7MT1; HCMT1; Hcm1p;
Function
Catalytic subunit of the mRNA-capping methyltransferase RNMT:RAMAC complex that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs (PubMed:9790902, PubMed:9705270, PubMed:10347220, PubMed:11114884, PubMed:22099306, PubMed:27422871).
Binds RNA containing 5'-terminal GpppC (PubMed:11114884).
Biological Process
Biological Process 7-methylguanosine mRNA cappingManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process cellular response to leukemia inhibitory factorIEA:Ensembl
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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