RRBP1

This gene encodes a ribosome-binding protein of the endoplasmic reticulum (ER) membrane. Studies suggest that this gene plays a role in ER proliferation, secretory pathways and secretory cell differentiation, and mediation of ER-microtubule interactions. Alternative splicing has been observed and protein isoforms are characterized by regions of N-terminal decapeptide and C-terminal heptad repeats. Splicing of the tandem repeats results in variations in ribosome-binding affinity and secretory function. The full-length nature of variants which differ in repeat length has not been determined. Pseudogenes of this gene have been identified on chromosomes 3 and 7, and RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome, the result of a mutation in a nearby gene on chromosome 20p12. [provided by RefSeq, Apr 2012]
Full Name
Ribosome Binding Protein 1
Function
Acts as a ribosome receptor and mediates interaction between the ribosome and the endoplasmic reticulum membrane.
Biological Process
Biological Process osteoblast differentiationManual Assertion Based On ExperimentHDA:UniProtKB
Biological Process protein transportIEA:UniProtKB-KW
Biological Process translationManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Endoplasmic reticulum membrane
Topology
Lumenal: 1-7
Helical: 8-28
Cytoplasmic: 29-1410
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Anti-RRBP1 antibodies

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Mouse Anti-RRBP1 Recombinant Antibody (P5610) (CBMAB-R3657-CN)

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Target: RRBP1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: P5610
Application*: ICC, IF, WB
Datasheet SDS

Mouse Anti-RRBP1 Recombinant Antibody (P1611) (CBMAB-R3656-CN)

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Target: RRBP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: P1611
Application*: WB
Datasheet SDS

Mouse Anti-RRBP1 Recombinant Antibody (5610) (CBMAB-R3655-CN)

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Target: RRBP1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 5610
Application*: WB, IF
Datasheet SDS

Mouse Anti-RRBP1 Recombinant Antibody (3F1) (CBMAB-R3654-CN)

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Target: RRBP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3F1
Application*: WB, IH
Datasheet SDS

Mouse Anti-RRBP1 Recombinant Antibody (1611) (CBMAB-R3653-CN)

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Target: RRBP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1611
Application*: WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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