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SAP130

SAP130 is a subunit of the histone deacetylase-dependent SIN3A (MIM 607776) corepressor complex.

Full Name

Sin3A Associated Protein 130

Function

Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes.

Biological Process

Biological Process negative regulation of cell migration1 PublicationIC:ComplexPortal
Biological Process negative regulation of stem cell population maintenance1 PublicationIC:ComplexPortal
Biological Process negative regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIMP:BHF-UCL
Biological Process negative regulation of transforming growth factor beta receptor signaling pathway1 PublicationIC:ComplexPortal
Biological Process positive regulation of stem cell population maintenance1 PublicationIC:ComplexPortal

Cellular Location

Nucleus

PTM

Acetylated.
Sumoylated with SUMO1.

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Anti-SAP130 antibodies

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Recombinant Mouse Anti-SAP130 Recombinant Antibody (1B10) (CBMAB-XB1023-YC)

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Target: SAP130

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human, Mouse

Clone: 1B10

Application*: E, IF, WB

Mouse Anti-SAP130 Recombinant Antibody (CBXS-5592) (CBMAB-S0470-CQ)

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Target: SAP130

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBXS-5592

Application*: E, WB, IC

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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