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Mouse Anti-SAP130 Recombinant Antibody (CBXS-5592) (CBMAB-S0470-CQ)

This product is a mouse antibody that recognizes SAP130. The antibody CBXS-5592 can be used for immunoassay techniques such as: ELISA, WB, IC.
See all SAP130 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-5592
Antibody Isotype
IgG1, κ
Application
ELISA, WB, IC

Basic Information

Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Sin3A Associated Protein 130
Introduction
SAP130 is a subunit of the histone deacetylase (see HDAC1; MIM 601241)-dependent SIN3A (MIM 607776) corepressor complex (Fleischer et al., 2003 [PubMed 12724404]).
Entrez Gene ID
79595
UniProt ID
Q9H0E3
Alternative Names
Sin3A Associated Protein 130; 130 KDa Sin3-Associated Polypeptide; Sin3A-Associated Protein, 130kDa; Sin3-Associated Polypeptide P130;
Function
Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes.
Biological Process
Biological Process negative regulation of cell migration1 PublicationIC:ComplexPortal
Biological Process negative regulation of stem cell population maintenance1 PublicationIC:ComplexPortal
Biological Process negative regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIMP:BHF-UCL
Biological Process negative regulation of transforming growth factor beta receptor signaling pathway1 PublicationIC:ComplexPortal
Biological Process positive regulation of stem cell population maintenance1 PublicationIC:ComplexPortal
Cellular Location
Nucleus
PTM
Acetylated.
Sumoylated with SUMO1.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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