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Recombinant Mouse Anti-SAP130 Recombinant Antibody (1B10) (CBMAB-XB1023-YC)

Provided herein is a Mouse Recombinant Antibody against Sin3A Associated Protein 130. The antibody can be used for immunoassay techniques, such as ELISA, IF, WB.
See all SAP130 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse
Clone
1B10
Antibody Isotype
IgG1, κ
Application
ELISA, IF, WB

Basic Information

Immunogen
Synthetic peptide coupled to Ovalbumin (RLPPNTNDEVDEDPTGNKAL) corresponding to aa 1057-1076 of human SAP130
Specificity
Human, Mouse
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Sin3A Associated Protein 130
Introduction
SAP130 is a subunit of the histone deacetylase-dependent SIN3A (MIM 607776) corepressor complex.
Entrez Gene ID
Human79595
Mouse269003
UniProt ID
HumanQ9H0E3
MouseQ8BIH0
Alternative Names
Sin3A Associated Protein 130; 130 KDa Sin3-Associated Polypeptide; Sin3A-Associated Protein, 130kDa; Sin3-Associated Polypeptide P130;
Function
Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes.
Biological Process
Biological Process negative regulation of cell migration1 PublicationIC:ComplexPortal
Biological Process negative regulation of stem cell population maintenance1 PublicationIC:ComplexPortal
Biological Process negative regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIMP:BHF-UCL
Biological Process negative regulation of transforming growth factor beta receptor signaling pathway1 PublicationIC:ComplexPortal
Biological Process positive regulation of stem cell population maintenance1 PublicationIC:ComplexPortal
Cellular Location
Nucleus
PTM
Acetylated.
Sumoylated with SUMO1.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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