SAXO1

SAXO1 (Stabilizer Of Axonemal Microtubules 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include microtubule binding. An important paralog of this gene is SAXO2.

Full Name

Stabilizer Of Axonemal Microtubules 1

Function

May play a role in the regulation of cilium length. Stabilizes microtubules at low temperature.

Biological Process

Biological Process cell projection organizationIEA:UniProtKB-KW
Biological Process cellular response to coldManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process cold acclimationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process positive regulation of cilium assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process protein stabilizationManual Assertion Based On ExperimentIDA:UniProtKB

Cellular Location

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole
Cytoplasm, cytoskeleton, cilium basal body
Cytoplasm, cytoskeleton, cilium axoneme
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Cytoplasm, cytoskeleton, flagellum axoneme
In multi-ciliated cells, localizes to the basal bodies and in non-ciliated cells, to the centrosome. In spermatozoa, colocalizes with microtubules along the length of the axoneme from its proximal end to its distal tip and with tubulin at the distal end of the flagellum and at the proximal centriole.