SEPHS2

This gene encodes an enzyme that synthesizes selenophosphate from selenide and ATP. Selenophosphate is the selenium donor used to synthesize selenocysteine, which is co-translationally incorporated into selenoproteins at in-frame UGA codons. This protein itself contains a selenocysteine residue in its predicted active site. The 3' UTR of the gene has a stem-loop secondary structure called a selenocysteine insertion sequence (SECIS) element, which allows UGA to direct the incorporation of selenocysteine rather than signal a translational stop. Alternatively spliced transcripts have been identified, but their biological validity has not been determined. [provided by RefSeq]
Full Name
selenophosphate synthetase 2
Function
Synthesizes selenophosphate from selenide and ATP.
Biological Process
Biological Process phosphorylationIEA:UniProtKB-KW
Biological Process selenium compound metabolic processIEA:Ensembl
Biological Process selenocysteine biosynthetic processManual Assertion Based On ExperimentIBA:GO_Central
Biological Process selenocysteine metabolic processTAS:Reactome
Cellular Location
cytoplasm
cytosol
PTM
Truncated SEPHS2 proteins produced by failed UGA/Sec decoding are ubiquitinated by the CRL2(KLHDC3) complex, which recognizes the glycine (Gly) at the C-terminus of truncated SEPHS2 proteins.
View more

Anti-SEPHS2 antibodies

+ Filters
Loading...

Mouse Anti-SEPHS2 Recombinant Antibody (2G9) (CBMAB-A7975-LY)

Go to compare Compare
Target: SEPHS2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 2G9
Application*: WB, E
Mouse Anti-SEPHS2 Recombinant Antibody (2G9)
Datasheet SDS

Mouse Anti-SEPHS2 Recombinant Antibody (CBXS-4637) (CBMAB-S1876-CQ)

Go to compare Compare
Target: SEPHS2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXS-4637
Application*: E, P, WB
Mouse Anti-SEPHS2 Recombinant Antibody (CBXS-4637)
Datasheet SDS

Human SEPHS2 ELISA Kit (V2LY-0626-LY3716)

Go to compare Compare
Target: SEPHS2
Sensitivity: 0.011 ng/mL
Detection Range: 0.02-7 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Human SEPHS2 ELISA Kit
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products Hot products

For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
online inquiry
Online Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.