SERPINB5

SERPINB5 (Serpin Family B Member 5) is a Protein Coding gene. Diseases associated with SERPINB5 include Syringoma and Bone Squamous Cell Carcinoma. Among its related pathways are Direct p53 effectors and DNA Damage Response. Gene Ontology (GO) annotations related to this gene include serine-type endopeptidase inhibitor activity. An important paralog of this gene is SERPINB1.

Full Name

serpin peptidase inhibitor, clade B (ovalbumin), member 5

Function

Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.

Biological Process

Biological Process extracellular matrix organizationIEA:Ensembl
Biological Process morphogenesis of an epitheliumIEA:Ensembl
Biological Process negative regulation of endopeptidase activityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process prostate gland morphogenesisIEA:Ensembl
Biological Process regulation of epithelial cell proliferationIEA:Ensembl

Cellular Location

Secreted, extracellular space

Anti-SERPINB5 antibodies

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Mouse Anti-SERPINB5 Recombinant Antibody (1F7) (CBMAB-A8000-LY)

Datasheet

SDS

Target: SERPINB5

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 1F7

Application*: WB, E

Mouse Anti-SERPINB5 Recombinant Antibody (CBXS-2787) (CBMAB-S5538-CQ)

Datasheet

SDS

Target: SERPINB5

Host: Mouse

Specificity: Human

Clone: CBXS-2787

Application*: E, IF, WB

Rat Anti-SERPINB5 Recombinant Antibody (CBXS-1758) (CBMAB-S4580-CQ)

Datasheet

SDS

Target: SERPINB5

Host: Rat

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBXS-1758

Application*: WB, IP

Datasheet

SDS

Target: SERPINB5

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: CBFYM-3119

Application*: E, IF, WB

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)