SIGLECH

Siglec-H, has recently been identified as a specific surface marker for pDCs in mice. Siglec-H is endocytosed and can mediate the uptake of antigens for processing and presentation.

Full Name

Sialic Acid Binding Ig-Like Lectin H

Biological Process

Biological Process cell adhesionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process establishment of localization in cellManual Assertion Based On ExperimentIDA:MGI
Biological Process receptor-mediated endocytosisManual Assertion Based On ExperimentIDA:MGI

Cellular Location

cell surface
integral component of membrane
plasma membrane

Topology

Helical: 250-270

Anti-SIGLECH antibodies

Rat Anti-SIGLECH Recombinant Antibody (CBXS-1911) (CBMAB-S0137-CQ)

Datasheet

SDS

Target: SIGLECH

Host: Rat

Antibody Isotype: IgG1

Specificity: Mouse

Clone: CBXS-1911

Application*: F

Rat Anti-SIGLECH (AA 286-304) Recombinant Antibody (CBXS-4281) (CBMAB-S0234-CQ)

Datasheet

SDS

Target: SIGLECH

Host: Rat

Antibody Isotype: IgG2a, κ

Specificity: Mouse

Clone: CBXS-4281

Application*: F, P, WB

Rat Anti-SIGLECH Recombinant Antibody (CBXS-4282) (CBMAB-S0235-CQ)

Datasheet

SDS

Target: SIGLECH

Host: Rat

Antibody Isotype: IgG2a, κ

Specificity: Mouse

Clone: CBXS-4282

Application*: P

Human Anti-SIGLECH Recombinant Antibody (CBXS-3573) (CBMAB-S0388-CQ)

Datasheet

SDS

Target: SIGLECH

Host: Human

Antibody Isotype: IgG1

Specificity: Mouse

Clone: CBXS-3573

Application*: F

Rat Anti-SIGLECH Recombinant Antibody (440c) (CBMAB-S0454-CQ)

Datasheet

SDS

Target: SIGLECH

Host: Rat

Antibody Isotype: IgG2b

Specificity: Mouse

Clone: 440c

Application*: F, FN, C

Rat Anti-SIGLECH (AA 109-309) Recombinant Antibody (ABM2B55) (CBMAB-S2915-CQ)

Datasheet

SDS

Target: SIGLECH

Host: Rat

Antibody Isotype: IgG2a, κ

Specificity: Mouse

Clone: ABM2B55

Application*: WB

Rat Anti-SIGLECH Recombinant Antibody (CBXS-2432) (CBMAB-S5189-CQ)

Datasheet

SDS

Target: SIGLECH

Host: Rat

Antibody Isotype: IgG2b

Specificity: Mouse

Clone: CBXS-2432

Application*: F, IH

Rat Anti-SIGLECH Recombinant Antibody (CBFYA-0036) (CBMAB-X0055-FY)

Datasheet

SDS

Target: SIGLECH

Host: Rat

Antibody Isotype: IgG2b

Specificity: Mouse

Clone: CBFYA-0036

Application*: F, C, FN, P

Recombinant Rat Anti-Siglech Antibody (CBHb055) (CBMAB-Hb967-LY)

Datasheet

SDS

Target: SIGLECH

Host: Rat

Antibody Isotype: IgG2b

Specificity: Mouse

Clone: CBHb055

Application*: FC, IHC-F, FuncS, IHC-P

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)