SPIC

The protein encoded by this gene regulates the development of red pulp macrophages, which are necessary for iron homeostasis and the recycling of red blood cells.
Full Name
Spi-C Transcription Factor
Function
Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression (By similarity).
Biological Process
Biological Process blastocyst developmentIEA:Ensembl
Biological Process cell differentiationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Nucleus
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Anti-SPIC antibodies

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Mouse Anti-SPIC Monoclonal Antibody (2C5) (CBMAB-0180-LY)

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Target: SPIC
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 2C5
Application*: IP, M
Datasheet SDS

Mouse Anti-SPIC Recombinant Antibody (CBXS-2091) (CBMAB-S4856-CQ)

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Target: SPIC
Host: Mouse
Specificity: Human
Clone: CBXS-2091
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-SPIC Monoclonal Antibody (2C11) (CBMAB-0179-LY)

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Target: SPIC
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 2C11
Application*: IP, M
Datasheet SDS

Mouse Anti-SPIC Monoclonal Antibody (1F10) (CBMAB-0178-LY)

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Target: SPIC
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 1F10
Application*: IP, M
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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