SYNGR2
This gene encodes an integral membrane protein containing four transmembrane regions and a C-terminal cytoplasmic tail that is tyrosine phosphorylated. The exact function of this protein is unclear, but studies of a similar rat protein suggest that it may play a role in regulating membrane traffic in non-neuronal cells. The gene belongs to the synaptogyrin gene family. [provided by RefSeq]
Full Name
synaptogyrin 2
Function
May play a role in regulated exocytosis. In neuronal cells, modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in the formation and/or the maturation of this vesicles. May also play a role in GLUT4 storage and transport to the plasma membrane.
(Microbial infection) May play a role in the assembly of cytoplasmic inclusion bodies required for SFTS phlebovirus replication.
(Microbial infection) May play a role in the assembly of cytoplasmic inclusion bodies required for SFTS phlebovirus replication.
Biological Process
Biological Process regulated exocytosisISS:UniProtKB
Biological Process synaptic vesicle membrane organizationISS:UniProtKB
Biological Process synaptic vesicle membrane organizationISS:UniProtKB
PTM
May be tyrosine phosphorylated by Src.
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Anti-SYNGR2 antibodies
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Target: SYNGR2
Host: Mouse
Antibody Isotype: IgG3, κ
Specificity: Human
Clone: 5C3
Application*: WB, E
Target: SYNGR2
Host: Mouse
Antibody Isotype: IgG3, κ
Specificity: Human
Clone: 1G7
Application*: WB, E
Target: SYNGR2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat, Mouse
Clone: 24/Cellugyrin
Application*: WB, IF
Target: SYNGR2
Sensitivity: 0.02 ng/mL
Detection Range: 0.05-15 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Target: SYNGR2
Host: Mouse
Specificity: Human
Clone: CBXS-5156
Application*: WB, IP, E
Target: SYNGR2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat, Mouse
Clone: CBFYC-3143
Application*: WB, BI, IF
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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