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SYNJ2

Synaptojanin-2 is a ubiquitously expressed inositol polyphosphate 5-phosphatase (Malecz et al., 2000 [PubMed 11084340]).[supplied by OMIM

Full Name

SYNJ2

Function

Inositol 5-phosphatase which may be involved in distinct membrane trafficking and signal transduction pathways. May mediate the inhibitory effect of Rac1 on endocytosis.

Biological Process

Biological Process brain developmentIBA:GO_Central1 Publication
Biological Process inositol phosphate dephosphorylationIBA:GO_Central1 Publication
Biological Process membrane organizationTAS:Reactome
Biological Process phosphatidylinositol biosynthetic processTAS:Reactome
Biological Process phosphatidylinositol dephosphorylationIBA:GO_Central1 Publication
Biological Process synaptic vesicle endocytosisIBA:GO_Central1 Publication

Cellular Location

Cytoplasm
Cell membrane
Membrane raft
Presynapse
Cytoplasm, cytoskeleton
Localizes at presynapse terminals in brain and at bundles of microtubules surrounding the nucleus in the elongating spermatids corresponding to the manchette (By similarity).
Translocates from the cytoplasm to membrane ruffles in a RAC1-dependent manner (PubMed:11084340).

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Anti-SYNJ2 antibodies

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Mouse Anti-SYNJ2 Recombinant Antibody (2H8) (CBMAB-A8813-LY)

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Target: SYNJ2

Host: Mouse

Antibody Isotype: IgG3, κ

Specificity: Human

Clone: 2H8

Application*: WB, E

Mouse Anti-SYNJ2 Recombinant Antibody (2B11) (CBMAB-A8812-LY)

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Target: SYNJ2

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 2B11

Application*: WB, E

Rabbit Anti-SYNJ2 Recombinant Antibody (CBXS-1456) (CBMAB-S4313-CQ)

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Target: SYNJ2

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: CBXS-1456

Application*: WB, IP, IC

SYNJ2 Matched Antibody Pair (1175) (APMAB-1175LY)

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Target: SYNJ2

Specificity: Human

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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