SYNJ2

Synaptojanin-2 is a ubiquitously expressed inositol polyphosphate 5-phosphatase (Malecz et al., 2000 [PubMed 11084340]).[supplied by OMIM
Full Name
SYNJ2
Function
Inositol 5-phosphatase which may be involved in distinct membrane trafficking and signal transduction pathways. May mediate the inhibitory effect of Rac1 on endocytosis.
Biological Process
Biological Process brain developmentIBA:GO_Central1 Publication
Biological Process inositol phosphate dephosphorylationIBA:GO_Central1 Publication
Biological Process membrane organizationTAS:Reactome
Biological Process phosphatidylinositol biosynthetic processTAS:Reactome
Biological Process phosphatidylinositol dephosphorylationIBA:GO_Central1 Publication
Biological Process synaptic vesicle endocytosisIBA:GO_Central1 Publication
Cellular Location
Cytoplasm
Cell membrane
Membrane raft
Presynapse
Cytoplasm, cytoskeleton
Localizes at presynapse terminals in brain and at bundles of microtubules surrounding the nucleus in the elongating spermatids corresponding to the manchette (By similarity).
Translocates from the cytoplasm to membrane ruffles in a RAC1-dependent manner (PubMed:11084340).
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Anti-SYNJ2 antibodies

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Mouse Anti-SYNJ2 Recombinant Antibody (2H8) (CBMAB-A8813-LY)

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Target: SYNJ2
Host: Mouse
Antibody Isotype: IgG3, κ
Specificity: Human
Clone: 2H8
Application*: WB, E
Datasheet SDS

Mouse Anti-SYNJ2 Recombinant Antibody (2B11) (CBMAB-A8812-LY)

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Target: SYNJ2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2B11
Application*: WB, E
Datasheet SDS

Rabbit Anti-SYNJ2 Recombinant Antibody (CBXS-1456) (CBMAB-S4313-CQ)

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Target: SYNJ2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXS-1456
Application*: WB, IP, IC
Datasheet SDS

SYNJ2 Matched Antibody Pair (1175) (APMAB-1175LY)

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Target: SYNJ2
Specificity: Human
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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