TACSTD2
Tacstd2 may play a role as a growth factor receptor.
Full Name
TACSTD2
Function
May function as a growth factor receptor.
Biological Process
Biological Process negative regulation of branching involved in ureteric bud morphogenesisISS:UniProtKB
Biological Process negative regulation of cell motilityISS:UniProtKB
Biological Process negative regulation of epithelial cell migrationISS:UniProtKB
Biological Process negative regulation of ruffle assemblyISS:UniProtKB
Biological Process negative regulation of stress fiber assemblyISS:UniProtKB
Biological Process negative regulation of substrate adhesion-dependent cell spreadingISS:UniProtKB
Biological Process positive regulation of stem cell differentiationIBA:GO_Central1 Publication
Biological Process regulation of epithelial cell proliferationIEA:Ensembl
Biological Process response to stimulusIEA:UniProtKB-KW
Biological Process ureteric bud morphogenesisIEA:Ensembl
Biological Process visual perceptionTAS:ProtInc1 Publication
Biological Process negative regulation of cell motilityISS:UniProtKB
Biological Process negative regulation of epithelial cell migrationISS:UniProtKB
Biological Process negative regulation of ruffle assemblyISS:UniProtKB
Biological Process negative regulation of stress fiber assemblyISS:UniProtKB
Biological Process negative regulation of substrate adhesion-dependent cell spreadingISS:UniProtKB
Biological Process positive regulation of stem cell differentiationIBA:GO_Central1 Publication
Biological Process regulation of epithelial cell proliferationIEA:Ensembl
Biological Process response to stimulusIEA:UniProtKB-KW
Biological Process ureteric bud morphogenesisIEA:Ensembl
Biological Process visual perceptionTAS:ProtInc1 Publication
Cellular Location
Membrane
Involvement in disease
Corneal dystrophy, gelatinous drop-like (GDLD):
A form of lattice corneal dystrophy, a class of inherited stromal amyloidoses characterized by pathognomonic branching lattice figures in the cornea. GDLD is an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness. Clinical manifestations, which appear in the first decade of life, include blurred vision, photophobia, and foreign-body sensation. By the third decade, raised, yellowish-gray, gelatinous masses severely impair visual acuity.
A form of lattice corneal dystrophy, a class of inherited stromal amyloidoses characterized by pathognomonic branching lattice figures in the cornea. GDLD is an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness. Clinical manifestations, which appear in the first decade of life, include blurred vision, photophobia, and foreign-body sensation. By the third decade, raised, yellowish-gray, gelatinous masses severely impair visual acuity.
Topology
Extracellular: 27-274
Helical: 275-297
Cytoplasmic: 298-323
Helical: 275-297
Cytoplasmic: 298-323
PTM
The N-terminus is blocked.
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Anti-TACSTD2 antibodies
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CompareTarget: TACSTD2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: D1W5W
Application*: WB, IP
Target: Tacstd2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBYJT-1802
Application*: E
Target: TACSTD2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1799
Application*: F, IC, P, IP, WB
Target: Tacstd2
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: CBYJT-1805
Application*: WB
Target: Tacstd2
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBYJT-1804
Application*: WB
Target: Tacstd2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBYJT-1803
Application*: E
Target: Tacstd2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBYJT-1801
Application*: P
Target: TACSTD2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYJT-1800
Application*: E, F, IC, IF, P, IP, WB
Target: TACSTD2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1798
Application*: WB, F, MC
Target: TACSTD2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYJT-1797
Application*: WB, F, MC
Target: TACSTD2
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: CBYJT-1796
Application*: F, WB
Target: TACSTD2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-1795
Application*: WB, E, P
Target: TACSTD2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJT-1794
Application*: F
Target: TACSTD2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJT-1793
Application*: F
Target: TACSTD2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-1792
Application*: E, IF, IC
Target: TACSTD2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-1791
Application*: E, F, IC, IF
Target: TACSTD2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 11BA41
Application*: E, WB
Target: TACSTD2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 11BA40
Application*: E, WB
Target: TACSTD2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 11BA39
Application*: E, WB
Target: TACSTD2
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-270
Tag: His Tag
Target: TACSTD2
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-270
Tag: His Tag
Target: TACSTD2
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-270
Tag: hFc Tag
Target: TACSTD2
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-274
Tag: His & hFc Tag
Target: TACSTD2
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-274
Tag: His Tag
Target: TACSTD2
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-274
Tag: His Tag
Target: TACSTD2
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-274
Tag: His & AVI Tag
Target: TACSTD2
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-274
Tag: hFc Tag
Target: TACSTD2
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-274
Tag: hFc & AVI Tag
Target: TACSTD2
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-272
Tag: His Tag
Target: TACSTD2
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: 10B10
Application*: E
Target: TACSTD2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBT2103
Application*: WB, IH, F
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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