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Mouse Anti-TACSTD2 Recombinant Antibody (CBYJT-1800) (CBMAB-T0862-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TACSTD2 (Tumor Associated Calcium Signal Transducer 2). The antibody can be used for immunoassay techniques, such as ELISA, FC, ICC, IF, IHC-P, IP, WB.
See all TACSTD2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-1800
Antibody Isotype
IgG2a, κ
Application
ELISA, FC, ICC, IF, IHC-P, IP, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.2
Preservative
0.09% Sodium Azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
TACSTD2
Introduction
This intronless gene encodes a carcinoma-associated antigen. TACSTD2 is a cell surface receptor that transduces calcium signals. Mutations of TACSTD2 have been associated with gelatinous drop-like corneal dystrophy.
Entrez Gene ID
4070
UniProt ID
P09758
Alternative Names
EGP1; GP50; M1S1; EGP-1; TROP2; GA7331; GA733-1
Function
May function as a growth factor receptor.
Biological Process
Biological Process negative regulation of branching involved in ureteric bud morphogenesisISS:UniProtKB
Biological Process negative regulation of cell motilityISS:UniProtKB
Biological Process negative regulation of epithelial cell migrationISS:UniProtKB
Biological Process negative regulation of ruffle assemblyISS:UniProtKB
Biological Process negative regulation of stress fiber assemblyISS:UniProtKB
Biological Process negative regulation of substrate adhesion-dependent cell spreadingISS:UniProtKB
Biological Process positive regulation of stem cell differentiationIBA:GO_Central1 Publication
Biological Process regulation of epithelial cell proliferationIEA:Ensembl
Biological Process response to stimulusIEA:UniProtKB-KW
Biological Process ureteric bud morphogenesisIEA:Ensembl
Biological Process visual perceptionTAS:ProtInc1 Publication
Cellular Location
Membrane
Involvement in disease
Corneal dystrophy, gelatinous drop-like (GDLD):
A form of lattice corneal dystrophy, a class of inherited stromal amyloidoses characterized by pathognomonic branching lattice figures in the cornea. GDLD is an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness. Clinical manifestations, which appear in the first decade of life, include blurred vision, photophobia, and foreign-body sensation. By the third decade, raised, yellowish-gray, gelatinous masses severely impair visual acuity.
Topology
Extracellular: 27-274
Helical: 275-297
Cytoplasmic: 298-323
PTM
The N-terminus is blocked.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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