Human Recombinant TACSTD2 protein, ECD, hFc Tag (V2LY-0526-LY7415)

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Basic Information

Expressed Host
HEK293 Cells
Protein Species
Human
Tag
hFc Tag
Protein Construction
This product is Human Recombinant TACSTD2 protein, ECD, hFc Tag consist of Amino Acid: 1-274 and predicts a molecular mass of 54.6 kDa.
Molecule Mass
54.6 kDa
Protein Domain
ECD
Verified
HPLC
Sequence
Amino Acid: 1-274
Species
Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
≥95% as determined by SDS-PAGE. ≥95% as determined by SEC-HPLC.
Endotoxin
Please contact us for more information.
Format
Lyophilized
Reconstitution
Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.
Buffer
Lyophilized from sterile PBS
Preservative
None
Storage
Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
More Infomation

Target

Full Name
TACSTD2
Function
May function as a growth factor receptor.
Biological Process
Biological Process negative regulation of branching involved in ureteric bud morphogenesisISS:UniProtKB
Biological Process negative regulation of cell motilityISS:UniProtKB
Biological Process negative regulation of epithelial cell migrationISS:UniProtKB
Biological Process negative regulation of ruffle assemblyISS:UniProtKB
Biological Process negative regulation of stress fiber assemblyISS:UniProtKB
Biological Process negative regulation of substrate adhesion-dependent cell spreadingISS:UniProtKB
Biological Process positive regulation of stem cell differentiationIBA:GO_Central1 Publication
Biological Process regulation of epithelial cell proliferationIEA:Ensembl
Biological Process response to stimulusIEA:UniProtKB-KW
Biological Process ureteric bud morphogenesisIEA:Ensembl
Biological Process visual perceptionTAS:ProtInc1 Publication
Cellular Location
Membrane
Involvement in disease
Corneal dystrophy, gelatinous drop-like (GDLD):
A form of lattice corneal dystrophy, a class of inherited stromal amyloidoses characterized by pathognomonic branching lattice figures in the cornea. GDLD is an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness. Clinical manifestations, which appear in the first decade of life, include blurred vision, photophobia, and foreign-body sensation. By the third decade, raised, yellowish-gray, gelatinous masses severely impair visual acuity.
Topology
Extracellular: 27-274
Helical: 275-297
Cytoplasmic: 298-323
PTM
The N-terminus is blocked.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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