TEKT2
This gene product belongs to the tektin family of proteins. Tektins comprise a family of filament-forming proteins that are coassembled with tubulins to form ciliary and flagellar microtubules. This gene is expressed in the testis and its protein is localized to the flagella of the sperms, indicating that it may play a role in spermatogenesis. [provided by RefSeq]
Full Name
tektin 2 (testicular)
Function
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules.
Biological Process
Biological Process cilium assemblySource:GO_Central1 Publication
Biological Process cilium movement involved in cell motilitySource:GO_Central1 Publication
Biological Process flagellated sperm motilitySource:Ensembl
Biological Process inner dynein arm assemblySource:Ensembl
Biological Process cilium movement involved in cell motilitySource:GO_Central1 Publication
Biological Process flagellated sperm motilitySource:Ensembl
Biological Process inner dynein arm assemblySource:Ensembl
Cellular Location
Cytoplasm, cytoskeleton, cilium axoneme
Cytoplasm, cytoskeleton, flagellum axoneme
Cytoplasm, cytoskeleton, microtubule organizing center
Colocalized with CCDC172 at the perinuclear region.
Cytoplasm, cytoskeleton, flagellum axoneme
Cytoplasm, cytoskeleton, microtubule organizing center
Colocalized with CCDC172 at the perinuclear region.
PTM
Tyrosine phosphorylated.
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Anti-TEKT2 antibodies
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Target: TEKT2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYJT-2514
Application*: WB
Target: TEKT2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYJT-2513
Application*: E, WB
Target: TEKT2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-2512
Application*: WB
Target: TEKT2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-2511
Application*: WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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