TGFA

Tgfa acts as an EGF receptor ligand and inhibits apoptosis that results from epithelial detachment from the extracellular matrix.
Full Name
Transforming Growth Factor Alpha
Function
TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar.
Biological Process
Biological Process angiogenesisSource:Ensembl
Biological Process epidermal growth factor receptor signaling pathwaySource:GO_Central1 Publication
Biological Process ERBB2-EGFR signaling pathwaySource:MGI1 Publication
Biological Process hepatocyte proliferationSource:Ensembl
Biological Process intracellular signal transductionSource:GO_Central1 Publication
Biological Process mammary gland alveolus developmentSource:Ensembl
Biological Process negative regulation of apoptotic processSource:Ensembl
Biological Process positive regulation of cell divisionSource:UniProtKB-KW
Biological Process positive regulation of cell population proliferationSource:GO_Central1 Publication
Biological Process positive regulation of epidermal growth factor-activated receptor activitySource:HGNC-UCL1 Publication
Biological Process positive regulation of epithelial cell proliferationSource:HGNC-UCL1 Publication
Biological Process positive regulation of MAP kinase activitySource:HGNC-UCL1 Publication
Biological Process positive regulation of mitotic nuclear divisionSource:HGNC-UCL1 Publication
Biological Process response to xenobiotic stimulusSource:Ensembl
Biological Process wound healingSource:Ensembl
Cellular Location
Transforming growth factor alpha
Secreted, extracellular space
Protransforming growth factor alpha
Cell membrane
Topology
Extracellular: 24-98
Helical: 99-124
Cytoplasmic: 125-160
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Anti-TGFA antibodies

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Mouse Anti-Tgfa Recombinant Antibody (SPM357) (CBMAB-T1978-YJ)

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Target: TGFA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Rat, Human, Mouse, Cattle
Clone: SPM357
Application*: IF, IC, F
Datasheet SDS

Mouse Anti-Tgfa Recombinant Antibody (MF9) (CBMAB-T1977-YJ)

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Target: TGFA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Rat, Human, Mouse, Cattle
Clone: MF9
Application*: WB, F, IC, IF, IP, C
Datasheet SDS

Mouse Anti-Tgfa Recombinant Antibody (CBYJT-2759) (CBMAB-T1976-YJ)

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Target: TGFA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Rat, Human, Mouse, Cattle
Clone: CBYJT-2759
Application*: WB
Datasheet SDS

Mouse Anti-Tgfa Recombinant Antibody (CBYJT-2758) (CBMAB-T1975-YJ)

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Target: Tgfa
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Rat
Clone: CBYJT-2758
Application*: WB
Datasheet SDS

Mouse Anti-TGFA Recombinant Antibody (CBYJT-2757) (CBMAB-T1974-YJ)

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Target: TGFA
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Rat, Mouse
Clone: CBYJT-2757
Application*: WB, IP, IF
Datasheet SDS

Mouse Anti-TGFA Recombinant Antibody (TG86) (CBMAB-T1972-YJ)

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Target: TGFA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Rabbit, Zebrafish
Clone: TG86
Application*: F, E, IC, IF, IP, P, C, MC
Datasheet SDS

Mouse Anti-TGFA Recombinant Antibody (P/T1) (CBMAB-T1970-YJ)

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Target: TGFA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Rabbit, Zebrafish
Clone: P/T1
Application*: F, E, IC, IF, IP, P, C, MC
Datasheet SDS

Mouse Anti-TGFA Recombinant Antibody (1E8-G6) (CBMAB-T1969-YJ)

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Target: TGFA
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human, Rabbit, Zebrafish
Clone: 1E8-G6
Application*: F, E, IC, IF, IP, P, C, MC
Datasheet SDS

Mouse Anti-TGFA Recombinant Antibody (213-4.4) (CBMAB-T1968-YJ)

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Target: TGFA
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse, Dog, Rat, Hamster
Clone: 213-4.4
Application*: IC, IF, IH, C, P
Datasheet SDS

Mouse Anti-TGFA Recombinant Antibody (TGFA/1119) (CBMAB-T1967-YJ)

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Target: TGFA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: TGFA/1119
Application*: F, P, IF, MC
Datasheet SDS

Mouse Anti-TGFA Recombinant Antibody (TFGFa-1) (CBMAB-T1966-YJ)

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Target: TGFA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: TFGFa-1
Application*: P, IF, IC
Datasheet SDS

Mouse Anti-TGFA Recombinant Antibody (1E8-269) (CBMAB-T1965-YJ)

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Target: TGFA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1E8-269
Application*: C, E, P
Datasheet SDS

Mouse Anti-TGFA Recombinant Antibody (CBFYE-1668) (CBMAB-E2337-FY)

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Target: TGFA
Host: Mouse
Specificity: Human
Clone: CBFYE-1668
Application*: WB, IC, P, C, E
Datasheet SDS

Mouse Anti-TGFA Monoclonal Antibody (SPM542) (CBMAB-1633-YC)

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Target: TGFA
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human, Rabbit, Zebrafish, Sheep
Clone: SPM542
Application*: F, IC, IF, C, P, IP
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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