TKT

This gene encodes a thiamine-dependent enzyme which plays a role in the channeling of excess sugar phosphates to glycolysis in the pentose phosphate pathway. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2012]
Full Name
TKT Gene(Protein Coding) Transketolase
Function
Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
Biological Process
Biological Process glyceraldehyde-3-phosphate biosynthetic processSource:UniProtKB1 Publication
Biological Process pentose-phosphate shuntSource:UniProtKB1 Publication
Biological Process pentose-phosphate shunt, non-oxidative branchSource:GO_Central1 Publication
Biological Process regulation of growthSource:Ensembl
Biological Process ribose phosphate biosynthetic processSource:GO_Central1 Publication
Cellular Location
cytosol
endoplasmic reticulum membrane
extracellular exosome
nuclear body
nucleoplasm
peroxisome
vesicle
Involvement in disease
Short stature, developmental delay, and congenital heart defects (SDDHD):
An autosomal recessive syndrome characterized by short stature, developmental delay, intellectual disability and congenital heart defects including ventricular septal defect, atrial septal defect and patent foramen ovale. Cataract and uveitis are observed in some patients.
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Anti-TKT antibodies

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Mouse Anti-TKT Recombinant Antibody (CBYJT-3275) (CBMAB-T2560-YJ)

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Target: TKT
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CBYJT-3275
Application*: E, WB, IH, F
Datasheet SDS

Mouse Anti-TKT Recombinant Antibody (CBYJT-3274) (CBMAB-T2559-YJ)

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Target: TKT
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse
Clone: CBYJT-3274
Application*: E, WB, IH, IF, F
Datasheet SDS

Mouse Anti-TKT Recombinant Antibody (CBYJT-3273) (CBMAB-T2558-YJ)

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Target: TKT
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-3273
Application*: WB, IP, P, F, IC, IF, E
Datasheet SDS

Mouse Anti-TKT Recombinant Antibody (CBYJT-3272) (CBMAB-T2557-YJ)

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Target: TKT
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-3272
Application*: F, IF, P, WB
Datasheet SDS

Mouse Anti-TKT Recombinant Antibody (37-1B2) (CBMAB-0155-CN)

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Target: TKT
Host: Mouse
Antibody Isotype: IgG1
Specificity: Frog
Clone: 37-1B2
Application*: E
Datasheet SDS

Mouse Anti-TKT Recombinant Antibody (16-3C1) (CBMAB-0041-CN)

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Target: TKT
Host: Mouse
Antibody Isotype: IgG1
Specificity: Frog
Clone: 16-3C1
Application*: IH, WB
Datasheet SDS

Mouse Anti-TKT Recombinant Antibody (CF439) (CBMAB-FT083LY)

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Target: TKT
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CF439
Application*: ELISA, WB, IHC, FC
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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