Mouse Anti-TKT Recombinant Antibody (CBYJT-3274) (CBMAB-T2559-YJ)

Name: Mouse Anti-TKT Recombinant Antibody (CBYJT-3274)
SKU: CBMAB-T2559-YJ
Rating: 5 (1 reviews)

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Datasheet

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Basic Information

Host Animal

Mouse

Clone

CBYJT-3274

Application

ELISA, WB, IHC, IF, FC

Specificity

Human, Mouse

Antibody Isotype

IgG2b

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.4

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

TKT Gene(Protein Coding) Transketolase

Introduction

TKT is a thiamine-dependent enzyme which plays a role in the channeling of excess sugar phosphates to glycolysis in the pentose phosphate pathway.

Entrez Gene ID

Human	7086
Mouse	21881

UniProt ID

Human	P29401
Mouse	P40142

Alternative Names

Transketolase; EC 2.2.1.1; TK; Epididymis Secretory Protein Li 48; Epididymis Luminal Protein 107; Wernicke-Korsakoff Syndrome

Function

Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.

Biological Process

Biological Process glyceraldehyde-3-phosphate biosynthetic processSource:UniProtKB1 Publication
Biological Process pentose-phosphate shuntSource:UniProtKB1 Publication
Biological Process pentose-phosphate shunt, non-oxidative branchSource:GO_Central1 Publication
Biological Process regulation of growthSource:Ensembl
Biological Process ribose phosphate biosynthetic processSource:GO_Central1 Publication

Cellular Location

cytosol
endoplasmic reticulum membrane
extracellular exosome
nuclear body
nucleoplasm
peroxisome
vesicle

Involvement in disease

Short stature, developmental delay, and congenital heart defects (SDDHD):
An autosomal recessive syndrome characterized by short stature, developmental delay, intellectual disability and congenital heart defects including ventricular septal defect, atrial septal defect and patent foramen ovale. Cataract and uveitis are observed in some patients.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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