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Mouse Anti-TKT Recombinant Antibody (CBYJT-3273) (CBMAB-T2558-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TKT (Transketolase). The antibody can be used for immunoassay techniques, such as WB, IP, IHC-P, FC, ICC, IF, ELISA.
See all TKT antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-3273
Antibody Isotype
IgG1
Application
WB, IP, IHC-P, FC, ICC, IF, ELISA

Basic Information

Immunogen
Hela cell cytosol fraction
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
TKT Gene(Protein Coding) Transketolase
Introduction
TKT is a thiamine-dependent enzyme which plays a role in the channeling of excess sugar phosphates to glycolysis in the pentose phosphate pathway.
Entrez Gene ID
UniProt ID
Alternative Names
Transketolase; EC 2.2.1.1; TK; Epididymis Secretory Protein Li 48; Epididymis Luminal Protein 107; Wernicke-Korsakoff Syndrome
Function
Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
Biological Process
Biological Process glyceraldehyde-3-phosphate biosynthetic processSource:UniProtKB1 Publication
Biological Process pentose-phosphate shuntSource:UniProtKB1 Publication
Biological Process pentose-phosphate shunt, non-oxidative branchSource:GO_Central1 Publication
Biological Process regulation of growthSource:Ensembl
Biological Process ribose phosphate biosynthetic processSource:GO_Central1 Publication
Cellular Location
cytosol
endoplasmic reticulum membrane
extracellular exosome
nuclear body
nucleoplasm
peroxisome
vesicle
Involvement in disease
Short stature, developmental delay, and congenital heart defects (SDDHD):
An autosomal recessive syndrome characterized by short stature, developmental delay, intellectual disability and congenital heart defects including ventricular septal defect, atrial septal defect and patent foramen ovale. Cataract and uveitis are observed in some patients.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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