TMX1
TMX1 is a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. TMX1 has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and one transmembrane domain. Unlike most members of this gene family, it lacks a C-terminal ER-retention sequence. The mature membrane-bound protein can both oxidize and reduce disulfide bonds and acts selectively on membrane-associated polypeptides.
Full Name
Thioredoxin Related Transmembrane Protein 1
Function
May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions.
Biological Process
Response to endoplasmic reticulum stress
Topology
Extracellular: 27-180
Helical: 181-203
Cytoplasmic: 204-280
Helical: 181-203
Cytoplasmic: 204-280
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Anti-TMX1 antibodies
+ Filters
Target: TMX1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-3590
Application*: IF, P, WB
Target: TMX1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-3589
Application*: WB, IH
Target: TMX1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-3588
Application*: WB
Target: TMX1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-3587
Application*: WB
Target: TMX1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-3586
Application*: WB
Target: TMX1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-3585
Application*: IF, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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