TNFRSF19

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is highly expressed during embryonic development. It has been shown to interact with TRAF family members, and to activate JNK signaling pathway when overexpressed in cells. This receptor is capable of inducing apoptosis by a caspase-independent mechanism, and it is thought to play an essential role in embryonic development. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Full Name
TNFRSF19 Gene(Protein Coding) TNF Receptor Superfamily Member 19
Function
Can mediate activation of JNK and NF-kappa-B. May promote caspase-independent cell death.
Biological Process
Biological Process apoptotic process Source:UniProtKB1 Publication
Biological Process hair follicle development Source:Ensembl
Biological Process JNK cascade Source:UniProtKB1 Publication
Biological Process positive regulation of I-kappaB kinase/NF-kappaB signaling Source:GO_Central1 Publication
Biological Process positive regulation of JNK cascade Source:GO_Central1 Publication
Cellular Location
Membrane
Topology
Extracellular: 30-170
Helical: 171-191
Cytoplasmic: 192-423
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Anti-TNFRSF19 antibodies

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Target: TNFRSF19
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1H6
Application*: WB, E
Target: TNFRSF19
Host: Mouse
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBYJT-3792
Application*: WB, IP, IF, E
Target: Tnfrsf19
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBYJT-3791
Application*: WB
Target: Tnfrsf19
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBYJT-3790
Application*: E, WB
Target: Tnfrsf19
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBYJT-3789
Application*: EC
Target: TNFRSF19
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-3785
Application*: WB, IP, IF, E
Target: TNFRSF19
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-3784
Application*: F, MC
Target: TNFRSF19
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-3783
Application*: F, MC
Target: TNFRSF19
Host: Rat
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-3782
Application*: F
Target: TNFRSF19
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJT-3781
Application*: E, WB
Target: TNFRSF19
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJT-3780
Application*: E, WB
Target: TNFRSF19
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-3779
Application*: E
Target: TNFRSF19
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2450
Application*: F
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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