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Rat Anti-Tnfrsf19 Recombinant Antibody (CBYJT-3791) (CBMAB-T3175-YJ)

Provided herein is a Rat monoclonal antibody, which binds to Tnfrsf19 (Tumor Necrosis Factor Receptor Superfamily, Member 19). The antibody can be used for immunoassay techniques, such as WB.
See all Tnfrsf19 antibodies

Summary

Host Animal
Rat
Specificity
Mouse
Clone
CBYJT-3791
Antibody Isotype
IgG2a
Application
WB

Basic Information

Immunogen
S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse TROY/TNFRSF19, Glu30-Leu170, Accession # Q9JLL3
Specificity
Mouse
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, Trehalose
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 30-170

Target

Full Name
TNFRSF19 Gene(Protein Coding) TNF Receptor Superfamily Member 19
Introduction
Tnfrsf19 can mediate activation of c-Jun and NF-kappa-B. It may promote caspase-independent cell death (By similarity). Isoform 2 and isoform 3 may act as decoy receptors.
Entrez Gene ID
29820
UniProt ID
Q9JLL3
Alternative Names
TAJ; Troy; TRADE; AL023044; AW123854; TAJ-ALPHA
Function
Can mediate activation of JNK and NF-kappa-B. May promote caspase-independent cell death.
Biological Process
Biological Process apoptotic process Source:UniProtKB1 Publication
Biological Process hair follicle development Source:Ensembl
Biological Process JNK cascade Source:UniProtKB1 Publication
Biological Process positive regulation of I-kappaB kinase/NF-kappaB signaling Source:GO_Central1 Publication
Biological Process positive regulation of JNK cascade Source:GO_Central1 Publication
Cellular Location
Membrane
Topology
Extracellular: 30-170
Helical: 171-191
Cytoplasmic: 192-423
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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