Rat Anti-TNFRSF19 Recombinant Antibody (CBYJT-3782) (CBMAB-T3166-YJ)

Name: Rat Anti-TNFRSF19 Recombinant Antibody (CBYJT-3782)
SKU: CBMAB-T3166-YJ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Rat

Clone

CBYJT-3782

Application

Immunogen

Recombinant protein corresponding to aa1-168 of human TAJ fused at the cysteine-rich domain to the Fc portion of human IgG1

Specificity

Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS

Preservative

0.02% Sodium Azide

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

aa 1-168

More Infomation

Target

Full Name

TNFRSF19 Gene(Protein Coding) TNF Receptor Superfamily Member 19

Introduction

TNFRSF19 is a member of the TNF-receptor superfamily. It is highly expressed during embryonic development. It has been shown to interact with TRAF family members, and to activate JNK signaling pathway when overexpressed in cells. It is capable of inducing apoptosis by a caspase-independent mechanism, and it is thought to play an necessary role in embryonic development.

Entrez Gene ID

55504

UniProt ID

Q9NS68

Alternative Names

TNF Receptor Superfamily Member 19; Toxicity And JNK Inducer; TRADE; TROY; TAJ; Tumor Necrosis Factor Receptor Superfamily, Member 19; Tumor Necrosis Factor Receptor Superfamily Member 19; TAJ-Alpha

Function

Can mediate activation of JNK and NF-kappa-B. May promote caspase-independent cell death.

Biological Process

Biological Process apoptotic process Source:UniProtKB1 Publication
Biological Process hair follicle development Source:Ensembl
Biological Process JNK cascade Source:UniProtKB1 Publication
Biological Process positive regulation of I-kappaB kinase/NF-kappaB signaling Source:GO_Central1 Publication
Biological Process positive regulation of JNK cascade Source:GO_Central1 Publication

Cellular Location

Membrane

Topology

Extracellular: 30-170
Helical: 171-191
Cytoplasmic: 192-423

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Antibody Pairs

TNFRSF19 Matched Antibody Pair (1228) (CAT#: APMAB-1228LY)

TNFRSF19 Matched Antibody Pair (1229) (CAT#: APMAB-1229LY)

TNFRSF19 Matched Antibody Pair (1230) (CAT#: APMAB-1230LY)

Related Products

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TNFRSF19 Matched Antibody Pair (1228) (CAT#: APMAB-1228LY)

Mouse Anti-TNFRSF19 Recombinant Antibody (CBYJT-3783) (CAT#: CBMAB-T3167-YJ)

Mouse Anti-TNFRSF19 Recombinant Antibody (CBYJT-3784) (CAT#: CBMAB-T3168-YJ)

Rat Anti-Tnfrsf19 Recombinant Antibody (CBYJT-3791) (CAT#: CBMAB-T3175-YJ)

Mouse Anti-TNFRSF19 Recombinant Antibody (CBYJT-3785) (CAT#: CBMAB-T3169-YJ)

Rabbit Anti-Tnfrsf19 Recombinant Antibody (CBYJT-3790) (CAT#: CBMAB-T3174-YJ)

Mouse Anti-TNFRSF19 Recombinant Antibody (CBYJT-3780) (CAT#: CBMAB-T3164-YJ)

Mouse Anti-TNFRSF19 Recombinant Antibody (CBYJT-3779) (CAT#: CBMAB-T3163-YJ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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