TRAPPC4

TRAPPC4 (Trafficking Protein Particle Complex 4) is a Protein Coding gene. Among its related pathways are Metabolism of proteins and Transport to the Golgi and subsequent modification. Gene Ontology (GO) annotations related to TRAPPC4 include Rab guanyl-nucleotide exchange factor activity.
Full Name
trafficking protein particle complex 4
Function
Core component of the TRAPP complexes which has a function of guanine nucleotide exchange factor activity for Rab1 GTPase (Probable). Plays a role in vesicular transport from endoplasmic reticulum to Golgi and autophagy (PubMed:31794024).
May play a role in dendrite postsynaptic membrane trafficking (By similarity).
Biological Process
Biological Process autophagy Source:UniProtKB1 Publication
Biological Process COPII vesicle coating Source:ComplexPortal1 Publication
Biological Process dendrite development Source:UniProtKBBy Similarity
Biological Process endoplasmic reticulum to Golgi vesicle-mediated transport Source:UniProtKB1 Publication
Biological Process vesicle coating Source:ComplexPortal1 Publication
Biological Process vesicle tethering Source:ComplexPortal1 Publication
Cellular Location
Postsynaptic cell membrane
Golgi apparatus membrane
Endoplasmic reticulum
Vesicle
Associated with postsynaptic membranes and in intracellular cisterns and vesicles (Golgi).
Involvement in disease
Neurodevelopmental disorder with epilepsy, spasticity, and brain atrophy (NEDESBA):
An autosomal recessive disorder characterized by severely impaired global development apparent soon after birth, early-onset seizures, lack of psychomotor development, spastic quadriparesis, progressive cortical and cerebellar atrophy, and dysmorphic features, including microcephaly. Death in childhood may occur.
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Anti-TRAPPC4 antibodies

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Mouse Anti-TRAPPC4 Recombinant Antibody (2D5) (CBMAB-A9483-LY)

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Target: TRAPPC4
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 2D5
Application*: WB, E
Datasheet SDS

Mouse Anti-TRAPPC4 Recombinant Antibody (2D10) (CBMAB-A9482-LY)

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Target: TRAPPC4
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse
Clone: 2D10
Application*: WB, E
Datasheet SDS

Mouse Anti-TRAPPC4 Recombinant Antibody (CBYJT-4568) (CBMAB-T4081-YJ)

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Target: TRAPPC4
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse
Clone: CBYJT-4568
Application*: E, IF, WB
Datasheet SDS

Mouse Anti-TRAPPC4 Recombinant Antibody (CBYJT-4567) (CBMAB-T4080-YJ)

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Target: TRAPPC4
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYJT-4567
Application*: F, IF, WB
Datasheet SDS

Mouse Anti-TRAPPC4 Recombinant Antibody (CBYJT-4566) (CBMAB-T4079-YJ)

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Target: TRAPPC4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4566
Application*: WB
Datasheet SDS

Mouse Anti-TRAPPC4 Recombinant Antibody (CBYJT-4565) (CBMAB-T4078-YJ)

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Target: TRAPPC4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4565
Application*: WB
Datasheet SDS

Mouse Anti-TRAPPC4 Recombinant Antibody (CBYJT-4564) (CBMAB-T4077-YJ)

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Target: TRAPPC4
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYJT-4564
Application*: WB, IH, F
Datasheet SDS

Mouse Anti-TRAPPC4 Recombinant Antibody (CBYJT-4563) (CBMAB-T4076-YJ)

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Target: TRAPPC4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4563
Application*: F, IF, P, WB
Datasheet SDS

Mouse Anti-TRAPPC4 Recombinant Antibody (CBYJT-4562) (CBMAB-T4075-YJ)

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Target: TRAPPC4
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJT-4562
Application*: E, IC, IF, WB
Datasheet SDS

Mouse Anti-TRAPPC4 Recombinant Antibody (CBYJT-4561) (CBMAB-T4074-YJ)

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Target: TRAPPC4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4561
Application*: WB
Datasheet SDS

Mouse Anti-TRAPPC4 Recombinant Antibody (CBYJT-4560) (CBMAB-T4073-YJ)

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Target: TRAPPC4
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYJT-4560
Application*: WB
Datasheet SDS

Mouse Anti-TRAPPC4 Recombinant Antibody (CBYJT-4559) (CBMAB-T4072-YJ)

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Target: TRAPPC4
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYJT-4559
Application*: WB
Datasheet SDS

Mouse Anti-TRAPPC4 Recombinant Antibody (CBYJT-4558) (CBMAB-T4071-YJ)

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Target: TRAPPC4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4558
Application*: WB, IH, IF, F
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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