TSPAN6

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq]

tetraspanin 6

Biological Process negative regulation of NIK/NF-kappaB signaling Source:UniProtKB1 Publication
Biological Process negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway Source:UniProtKB1 Publication
Biological Process positive regulation of I-kappaB kinase/NF-kappaB signaling Source:UniProtKB1 Publication

Membrane

Cytoplasmic: 1-19
Helical: 20-40
Extracellular: 41-59
Helical: 60-80
Cytoplasmic: 81-93
Helical: 94-114
Extracellular: 115-208
Helical: 209-229
Cytoplasmic: 230-245