TSPAN6
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq]
Full Name
tetraspanin 6
Biological Process
Biological Process negative regulation of NIK/NF-kappaB signaling Source:UniProtKB1 Publication
Biological Process negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway Source:UniProtKB1 Publication
Biological Process positive regulation of I-kappaB kinase/NF-kappaB signaling Source:UniProtKB1 Publication
Biological Process negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway Source:UniProtKB1 Publication
Biological Process positive regulation of I-kappaB kinase/NF-kappaB signaling Source:UniProtKB1 Publication
Cellular Location
Membrane
Topology
Cytoplasmic: 1-19
Helical: 20-40
Extracellular: 41-59
Helical: 60-80
Cytoplasmic: 81-93
Helical: 94-114
Extracellular: 115-208
Helical: 209-229
Cytoplasmic: 230-245
Helical: 20-40
Extracellular: 41-59
Helical: 60-80
Cytoplasmic: 81-93
Helical: 94-114
Extracellular: 115-208
Helical: 209-229
Cytoplasmic: 230-245
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Anti-TSPAN6 antibodies
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Target: TSPAN6
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1H1
Application*: SE, E
Target: TSPAN6
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBYJT-5080
Application*: E
Target: TSPAN6
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-5079
Application*: E
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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