Search :
Sign in or Register  
Welcome Sign in or Don't have an account?Register

Mouse Anti-TSPAN6 Recombinant Antibody (CBYJT-5080) (CBMAB-T4658-YJ)


See all TSPAN6 antibodies
Online Inquiry

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-5080
Antibody Isotype
IgG2b, κ
Application
ELISA

Basic Information

Immunogen
Partial recombinant corresponding to aa115-209 from human TSPAN6 (AAH12389) with GST tag. MW of the GST tag alone is 26kD
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.2
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 115-209

Target

Full Name
tetraspanin 6
Introduction
TSPAN6 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. It mediate signal transduction events that function in the regulation of cell development, activation, growth and motility. TSPAN6 is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2 protein. It plays a role as a negative regulator of retinoic acid-inducible gene I-like receptor-mediated immune signaling via its interaction with the mitochondrial antiviral signaling-centered signalosome.
Entrez Gene ID
7105
UniProt ID
O43657
Alternative Names
Tetraspanin 6; Transmembrane 4 Superfamily Member 6; Putative NF-Kappa-B-Activating Protein 321; Tetraspanin TM4-D; A15 Homolog; TSPAN-6
Biological Process
Biological Process negative regulation of NIK/NF-kappaB signaling Source:UniProtKB1 Publication
Biological Process negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway Source:UniProtKB1 Publication
Biological Process positive regulation of I-kappaB kinase/NF-kappaB signaling Source:UniProtKB1 Publication
Cellular Location
Membrane
Topology
Cytoplasmic: 1-19
Helical: 20-40
Extracellular: 41-59
Helical: 60-80
Cytoplasmic: 81-93
Helical: 94-114
Extracellular: 115-208
Helical: 209-229
Cytoplasmic: 230-245
More Infomation
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-TSPAN6 Recombinant Antibody (CBYJT-5080)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Request bulk or custom quote Online Inquiry
Second antibody and isotype control

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Online Inquiry