Mouse Anti-TSPAN6 Recombinant Antibody (CBYJT-5080) (CBMAB-T4658-YJ)

Name: Mouse Anti-TSPAN6 Recombinant Antibody (CBYJT-5080)
SKU: CBMAB-T4658-YJ
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

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Basic Information

Host Animal

Mouse

Clone

CBYJT-5080

Application

ELISA

Immunogen

Partial recombinant corresponding to aa115-209 from human TSPAN6 (AAH12389) with GST tag. MW of the GST tag alone is 26kD

Specificity

Human

Antibody Isotype

IgG2b, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.2

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

aa 115-209

More Infomation

Target

Full Name

tetraspanin 6

Introduction

TSPAN6 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. It mediate signal transduction events that function in the regulation of cell development, activation, growth and motility. TSPAN6 is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2 protein. It plays a role as a negative regulator of retinoic acid-inducible gene I-like receptor-mediated immune signaling via its interaction with the mitochondrial antiviral signaling-centered signalosome.

Entrez Gene ID

7105

UniProt ID

O43657

Alternative Names

Tetraspanin 6; Transmembrane 4 Superfamily Member 6; Putative NF-Kappa-B-Activating Protein 321; Tetraspanin TM4-D; A15 Homolog; TSPAN-6

Biological Process

Biological Process negative regulation of NIK/NF-kappaB signaling Source:UniProtKB1 Publication
Biological Process negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway Source:UniProtKB1 Publication
Biological Process positive regulation of I-kappaB kinase/NF-kappaB signaling Source:UniProtKB1 Publication

Cellular Location

Membrane

Topology

Cytoplasmic: 1-19
Helical: 20-40
Extracellular: 41-59
Helical: 60-80
Cytoplasmic: 81-93
Helical: 94-114
Extracellular: 115-208
Helical: 209-229
Cytoplasmic: 230-245

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Mouse Anti-TSPAN6 Recombinant Antibody (1H1) (CAT#: CBMAB-A9585-LY)

Isotype control

For research use only. Not intended for any clinical use.

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