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Mouse Anti-TSPAN6 Recombinant Antibody (CBYJT-5079) (CBMAB-T4657-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TSPAN6 (Tetraspanin 6). The antibody can be used for immunoassay techniques, such as ELISA.
See all TSPAN6 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-5079
Antibody Isotype
IgG
Application
ELISA

Basic Information

Immunogen
TSPAN6 (AAH12389, aa115-208) partial recombinant protein with GST tag. MW of the GST tag alone is 26kD
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 115-208

Target

Full Name
tetraspanin 6
Introduction
TSPAN6 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. It mediate signal transduction events that function in the regulation of cell development, activation, growth and motility. TSPAN6 is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2 protein. It plays a role as a negative regulator of retinoic acid-inducible gene I-like receptor-mediated immune signaling via its interaction with the mitochondrial antiviral signaling-centered signalosome.
Entrez Gene ID
7105
UniProt ID
O43657
Alternative Names
Tetraspanin 6; Transmembrane 4 Superfamily Member 6; Putative NF-Kappa-B-Activating Protein 321; Tetraspanin TM4-D; A15 Homolog; TSPAN-6
Biological Process
Biological Process negative regulation of NIK/NF-kappaB signaling Source:UniProtKB1 Publication
Biological Process negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway Source:UniProtKB1 Publication
Biological Process positive regulation of I-kappaB kinase/NF-kappaB signaling Source:UniProtKB1 Publication
Cellular Location
Membrane
Topology
Cytoplasmic: 1-19
Helical: 20-40
Extracellular: 41-59
Helical: 60-80
Cytoplasmic: 81-93
Helical: 94-114
Extracellular: 115-208
Helical: 209-229
Cytoplasmic: 230-245
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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