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TXNDC5

This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal endoplasmic reticulum (ER)-signal sequence, three catalytically active thioredoxin domains and a C-terminal ER-retention sequence. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S5 gene. [provided by RefSeq, Dec 2016]
Full Name
TXNDC5
Function
Protein disulfide isomerase of the endoplasmic reticulum lumen involved in the formation of disulfide bonds in proteins. Can reduce insulin disulfide bonds.
Biological Process
Biological Process negative regulation of apoptotic process Source:UniProtKB1 Publication
Biological Process protein folding Source:GO_Central1 Publication
Cellular Location
Endoplasmic reticulum lumen
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Anti-TXNDC5 antibodies

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Mouse Anti-TXNDC5 Recombinant Antibody (2E7/7) (CBMAB-BR483LY)

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Target: TXNDC5
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 2E7/7
Application*: ELISA, IP, IF
Datasheet SDS

Mouse Anti-TXNDC5 Recombinant Antibody (CBYJT-5467) (CBMAB-T5078-YJ)

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Target: TXNDC5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Monkey, Mouse
Clone: CBYJT-5467
Application*: WB, IH
Datasheet SDS

Mouse Anti-TXNDC5 Recombinant Antibody (CBYJT-5466) (CBMAB-T5077-YJ)

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Target: TXNDC5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Monkey
Clone: CBYJT-5466
Application*: WB
Datasheet SDS

Mouse Anti-TXNDC5 Recombinant Antibody (CBYJT-5465) (CBMAB-T5076-YJ)

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Target: TXNDC5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Monkey
Clone: CBYJT-5465
Application*: WB
Datasheet SDS

Mouse Anti-TXNDC5 Recombinant Antibody (CBYJT-5464) (CBMAB-T5075-YJ)

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Target: TXNDC5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Monkey
Clone: CBYJT-5464
Application*: WB
Datasheet SDS

Mouse Anti-TXNDC5 Recombinant Antibody (CBYJT-5463) (CBMAB-T5074-YJ)

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Target: TXNDC5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Monkey
Clone: CBYJT-5463
Application*: WB
Datasheet SDS

Mouse Anti-TXNDC5 Recombinant Antibody (CBYJT-5462) (CBMAB-T5073-YJ)

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Target: TXNDC5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Monkey
Clone: CBYJT-5462
Application*: WB, IH
Datasheet SDS

Mouse Anti-TXNDC5 Recombinant Antibody (CBYJT-5461) (CBMAB-T5071-YJ)

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Target: TXNDC5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-5461
Application*: WB, IH
Datasheet SDS

Mouse Anti-TXNDC5 Recombinant Antibody (1C1) (CBMAB-T5070-YJ)

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Target: TXNDC5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1C1
Application*: WB
Datasheet SDS

Mouse Anti-TXNDC5 (AA 52-63) Recombinant Antibody (2E7/7) (CBMAB-E0410-FY)

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Target: TXNDC5
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 2E7/7
Application*: E, WB, P, IF, IP
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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