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Mouse Anti-TXNDC5 Recombinant Antibody (1C1) (CBMAB-T5070-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TXNDC5 (Thioredoxin Domain Containing 5). The antibody can be used for immunoassay techniques, such as WB.
See all TXNDC5 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1C1
Antibody Isotype
IgG1
Application
WB

Basic Information

Immunogen
Full length human recombinant protein of human TXNDC5(NP_071368) produced in HEK293T cell
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.3, 1% BSA, 50% Glycerol
Preservative
0.02% Sodium Azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
TXNDC5
Introduction
TXNDC5 is a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. TXNDC5 has an N-terminal endoplasmic reticulum (ER)-signal sequence, three catalytically active thioredoxin domains and a C-terminal ER-retention sequence. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis.
Entrez Gene ID
81567
UniProt ID
Q8NBS9
Alternative Names
Thioredoxin Domain Containing 5; Protein Disulfide Isomerase Family A, Member 15; Endoplasmic Reticulum Resident Protein 46; Thioredoxin-Like Protein P46; ER Protein 46; ERP46; Thioredoxin Domain Containing 5 (Endoplasmic Reticulum); Endothelial Protein Disulphide Isomerase; Thioredoxin Domain-Containing Protein 5; Endoplasmic Reticulum Protein ERp46
Function
Protein disulfide isomerase of the endoplasmic reticulum lumen involved in the formation of disulfide bonds in proteins. Can reduce insulin disulfide bonds.
Biological Process
Biological Process negative regulation of apoptotic process Source:UniProtKB1 Publication
Biological Process protein folding Source:GO_Central1 Publication
Cellular Location
Endoplasmic reticulum lumen
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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