UHMK1

The gene encodes a serine/threonine protein kinase that promotes cell cycle progression through G1 by phosphorylation of the cyclin-dependent kinase inhibitor 1B (p27Kip1), which causes nuclear export and degradation. The encoded protein is also thought to function in the adult nervous system and the gene has been associated with schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Full Name
U2AF homology motif (UHM) kinase 1
Function
Upon serum stimulation, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. May be involved in trafficking and/or processing of RNA (By similarity).
Biological Process
Biological Process neuron projection development Source:BHF-UCL
Biological Process peptidyl-serine phosphorylation Source:HGNC-UCL1 Publication
Biological Process positive regulation of translational initiation Source:BHF-UCL
Biological Process protein autophosphorylation Source:HGNC-UCL1 Publication
Biological Process regulation of cell cycle Source:HGNC-UCL1 Publication
Biological Process regulation of protein export from nucleus Source:HGNC-UCL1 Publication
Cellular Location
Nucleus
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Anti-UHMK1 antibodies

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Mouse Anti-UHMK1 Recombinant Antibody (2D3) (CBMAB-C4569-CN)

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Target: UHMK1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 2D3
Application*: FC, WB
Datasheet SDS

Mouse Anti-UHMK1 Recombinant Antibody (1H5) (CBMAB-C4568-CN)

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Target: UHMK1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1H5
Application*: E
Datasheet SDS

Mouse Anti-UHMK1 Recombinant Antibody (5E10) (CBMAB-K0958-LY)

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Target: UHMK1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat, Dog, Human, Monkey
Clone: 5E10
Application*: WB
Datasheet SDS

Mouse Anti-UHMK1 Recombinant Antibody (2H4) (CBMAB-K0957-LY)

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Target: UHMK1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Monkey
Clone: 2H4
Application*: WB, F, IH, IC/IF, P
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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