Mouse Anti-UHMK1 Recombinant Antibody (2H4) (CBMAB-K0957-LY)

Name: Mouse Anti-UHMK1 Recombinant Antibody (2H4)
SKU: CBMAB-K0957-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

2H4

Application

WB, FC, IHC, ICC/IF, IHC-P

Immunogen

Full length human recombinant protein of human UHMK1 (NP_787062) produced in HEK293T cell

Specificity

Human, Monkey

Antibody Isotype

IgG2b

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

U2AF homology motif (UHM) kinase 1

Introduction

The gene encodes a serine/threonine protein kinase that promotes cell cycle progression through G1 by phosphorylation of the cyclin-dependent kinase inhibitor 1B (p27Kip1), which causes nuclear export and degradation. The encoded protein is also thought to function in the adult nervous system and the gene has been associated with schizophrenia. Alternative splicing results in multiple transcript variants.

Entrez Gene ID

Human	127933
Monkey	720105

UniProt ID

Human	Q8TAS1
Monkey	F7CXW1

Alternative Names

KIS; KIST; P-CIP2

Function

Upon serum stimulation, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. May be involved in trafficking and/or processing of RNA (By similarity).

Biological Process

Biological Process neuron projection development Source:BHF-UCL
Biological Process peptidyl-serine phosphorylation Source:HGNC-UCL1 Publication
Biological Process positive regulation of translational initiation Source:BHF-UCL
Biological Process protein autophosphorylation Source:HGNC-UCL1 Publication
Biological Process regulation of cell cycle Source:HGNC-UCL1 Publication
Biological Process regulation of protein export from nucleus Source:HGNC-UCL1 Publication

Cellular Location

Nucleus

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Mouse Anti-UHMK1 Recombinant Antibody (5E10) (CAT#: CBMAB-K0958-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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