ULBP1
The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
Full Name
UL16 Binding Protein 1
Function
Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity.
Biological Process
Biological Process natural killer cell activation Source:UniProtKB1 Publication
Biological Process natural killer cell mediated cytotoxicity Source:UniProtKB1 Publication
Biological Process natural killer cell mediated cytotoxicity Source:UniProtKB1 Publication
Cellular Location
Cell membrane
Endoplasmic reticulum
In CMV-infected fibroblasts, detected in the endoplasmic reticulum/cis-Golgi.
Endoplasmic reticulum
In CMV-infected fibroblasts, detected in the endoplasmic reticulum/cis-Golgi.
View more
Anti-ULBP1 antibodies
+ Filters

Target: ULBP1
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 237104
Application*: FC
Target: ULBP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2940
Application*: F
Target: ULBP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2338
Application*: WB
Target: ULBP1
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: 14L965
Application*: FC, N
Target: ULBP1
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: 10K10
Application*: FC, N
Target: ULBP1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 170818
Application*: FC
Target: ULBP1
Host: Armenian Hamster
Antibody Isotype: IgG
Specificity: Mouse, Rat
Clone: CBFYM-3175
Application*: F, C
More Infomation
Hot products 
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot

Online Inquiry