ULBP1

The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
Full Name
UL16 Binding Protein 1
Function
Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity.
Biological Process
Biological Process natural killer cell activation Source:UniProtKB1 Publication
Biological Process natural killer cell mediated cytotoxicity Source:UniProtKB1 Publication
Cellular Location
Cell membrane
Endoplasmic reticulum
In CMV-infected fibroblasts, detected in the endoplasmic reticulum/cis-Golgi.
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Anti-ULBP1 antibodies

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Rat Anti-ULBP1 Recombinant Antibody (237104) (CBMAB-C1030-CN)

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Target: ULBP1
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 237104
Application*: FC
Datasheet SDS

Rabbit Anti-ULBP1 Recombinant Antibody (
13C8) (V2LY-0725-LY1216)

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Target: ULBP1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 13C8
Application*: E, WB
Datasheet SDS

Mouse Anti-ULBP1 Recombinant Antibody (CBT2940) (V2LY-0625-LY1396)

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Target: ULBP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2940
Application*: F
Datasheet SDS

Mouse Anti-ULBP1 Recombinant Antibody (CBT2338) (V2LY-0625-LY1297)

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Target: ULBP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2338
Application*: WB
Datasheet SDS

Mouse Anti-ULBP1 Recombinant Antibody (14L965) (CBMAB-C4584-CN)

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Target: ULBP1
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: 14L965
Application*: FC, N
Datasheet SDS

Mouse Anti-ULBP1 Recombinant Antibody (10K10) (CBMAB-C4583-CN)

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Target: ULBP1
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: 10K10
Application*: FC, N
Datasheet SDS

Mouse Anti-ULBP1 Recombinant Antibody (170818) (CBMAB-C1029-CN)

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Target: ULBP1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 170818
Application*: FC
Datasheet SDS

Armenian Hamster Anti-ULBP1 Recombinant Antibody (CBFYM-3175) (CBMAB-M3372-FY)

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Target: ULBP1
Host: Armenian Hamster
Antibody Isotype: IgG
Specificity: Mouse, Rat
Clone: CBFYM-3175
Application*: F, C
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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