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Mouse Anti-ULBP1 Recombinant Antibody (10K10) (CBMAB-C4583-CN)

This product is a Mouse antibody that recognizes ULBP1. The antibody 10K10 can be used for immunoassay techniques such as: FC, Neut.
See all ULBP1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
10K10
Antibody Isotype
IgG2
Application
FC, Neut

Basic Information

Immunogen
Human recombinant ULBP-1
Specificity
Human
Antibody Isotype
IgG2
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Buffer
PBS

Target

Full Name
UL16 Binding Protein 1
Introduction
The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
Entrez Gene ID
80329
UniProt ID
Q9BZM6
Alternative Names
UL16 Binding Protein 1; Retinoic Acid Early Transcript 1I; NKG2D Ligand 1; Alcan-Beta; NKG2DL1; N2DL-1; RAET1I; UL16-Binding Protein 1; N2DL1;
Function
Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity.
Biological Process
Biological Process natural killer cell activation Source:UniProtKB1 Publication
Biological Process natural killer cell mediated cytotoxicity Source:UniProtKB1 Publication
Cellular Location
Cell membrane
Endoplasmic reticulum
In CMV-infected fibroblasts, detected in the endoplasmic reticulum/cis-Golgi.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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