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Armenian Hamster Anti-ULBP1 Recombinant Antibody (CBFYM-3175) (CBMAB-M3372-FY)

This product is armenian hamster antibody that recognizes ULBP1. The antibody CBFYM-3175 can be used for immunoassay techniques such as: FC, IHC-Fr.
See all ULBP1 antibodies

Summary

Host Animal
Armenian Hamster
Specificity
Mouse, Rat
Clone
CBFYM-3175
Antibody Isotype
IgG
Application
FC, IHC-Fr

Basic Information

Specificity
Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Preservative
0.09% Sodium azide
Concentration
0.5 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
UL16 Binding Protein 1
Introduction
The protein encoded by this gene is a ligand of natural killer group 2, member D, an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene.
Entrez Gene ID
Mouse77777
Rat102547056
UniProt ID
MouseQ3MI26
Alternative Names
UL16 Binding Protein 1; Retinoic Acid Early Transcript 1I; NKG2D Ligand 1; Alcan-Beta; NKG2DL1; N2DL-1; RAET1I; UL16-Binding Protein 1; N2DL1
Function
Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity.
Biological Process
Biological Process natural killer cell activation Source:UniProtKB1 Publication
Biological Process natural killer cell mediated cytotoxicity Source:UniProtKB1 Publication
Cellular Location
Cell membrane
Endoplasmic reticulum
In CMV-infected fibroblasts, detected in the endoplasmic reticulum/cis-Golgi.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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