USP39

Plays a role in pre-mRNA splicing as a component of the U4/U6-U5 tri-snRNP, one of the building blocks of the spliceosome. Regulates AURKB mRNA levels, and thereby plays a role in cytokinesis and in the spindle checkpoint. Does not have ubiquitin-specific peptidase activity, but could be a competitor of ubiquitin C-terminal hydrolases (UCHs).
Full Name
ubiquitin specific peptidase 39
Function
Plays a role in pre-mRNA splicing as a component of the U4/U6-U5 tri-snRNP, one of the building blocks of the precatalytic spliceosome (PubMed:11350945, PubMed:26912367).
Regulates AURKB mRNA levels, and thereby plays a role in cytokinesis and in the spindle checkpoint. Does not have ubiquitin-specific peptidase activity (PubMed:18728397).
Biological Process
Biological Process cell cycle Source:UniProtKB-KW
Biological Process cell division Source:UniProtKB-KW
Biological Process mRNA processing Source:ProtInc1 Publication
Biological Process mRNA splicing, via spliceosome Source:UniProtKB1 Publication
Biological Process protein deubiquitination Source:InterPro
Biological Process RNA splicing Source:ProtInc1 Publication
Biological Process spliceosomal complex assembly Source:UniProtKB1 Publication
Cellular Location
Nucleus
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Anti-USP39 antibodies

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Mouse Anti-USP39 Recombinant Antibody (4G11) (CBMAB-A9829-LY)

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Target: USP39
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4G11
Application*: WB, E
Datasheet SDS

Rabbit Anti-USP39 Recombinant Antibody (CBXU-036) (CBMAB-U0152-CQ)

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Target: USP39
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBXU-036
Application*: WB, P, IC
Datasheet SDS

Rabbit Anti-USP39 Recombinant Antibody (CBXU-035) (CBMAB-U0151-CQ)

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Target: USP39
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: CBXU-035
Application*: WB, P, IC
Datasheet SDS

Mouse Anti-USP39 Recombinant Antibody (3205C5a) (CBMAB-U0060-CQ)

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Target: USP39
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3205C5a
Application*: DB, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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