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Mouse Anti-USP39 Recombinant Antibody (3205C5a) (CBMAB-U0060-CQ)

This product is a mouse antibody that recognizes USP39. The antibody 3205C5a can be used for immunoassay techniques such as: Dot, WB.
See all USP39 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
3205C5a
Antibody Isotype
IgG1
Application
Dot, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2, 1% BSA
Preservative
0.05% sodium azide
Concentration
0.1 mg/mL
Purity
>95% as determined by SDS-PAGE analysis
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
ubiquitin specific peptidase 39
Introduction
Plays a role in pre-mRNA splicing as a component of the U4/U6-U5 tri-snRNP, one of the building blocks of the spliceosome. Regulates AURKB mRNA levels, and thereby plays a role in cytokinesis and in the spindle checkpoint.
Entrez Gene ID
10713
UniProt ID
Q53GS9
Alternative Names
USP39; ubiquitin specific peptidase 39; ubiquitin specific protease 39; U4/U6.U5 tri-snRNP-associated protein 2; CGI 21; SAD1; small nuclear ribonucleoprotein 65kDa (U4/U6.U5); snRNP assembly defective 1 homolog (S.cerevisiae); SNRNP65; SAD1 homolog; SnRNP assembly defective 1 homolog; inactive ubiquitin-specific peptidase 39; U4/U6.U5 tri-snRNP-associated 65 kDa protein; 65K; CGI-21; HSPC332; FLJ33136; MGC75069
Function
Plays a role in pre-mRNA splicing as a component of the U4/U6-U5 tri-snRNP, one of the building blocks of the precatalytic spliceosome (PubMed:11350945, PubMed:26912367).
Regulates AURKB mRNA levels, and thereby plays a role in cytokinesis and in the spindle checkpoint. Does not have ubiquitin-specific peptidase activity (PubMed:18728397).
Biological Process
Biological Process cell cycle Source:UniProtKB-KW
Biological Process cell division Source:UniProtKB-KW
Biological Process mRNA processing Source:ProtInc1 Publication
Biological Process mRNA splicing, via spliceosome Source:UniProtKB1 Publication
Biological Process protein deubiquitination Source:InterPro
Biological Process RNA splicing Source:ProtInc1 Publication
Biological Process spliceosomal complex assembly Source:UniProtKB1 Publication
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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