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Rabbit Anti-USP39 Recombinant Antibody (CBXU-036) (CBMAB-U0152-CQ)

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Datasheet
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Basic Information

Host Animal
Rabbit
Clone
CBXU-036
Application
WB, IHC-P, ICC
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
ubiquitin specific peptidase 39
Introduction
Plays a role in pre-mRNA splicing as a component of the U4/U6-U5 tri-snRNP, one of the building blocks of the spliceosome. Regulates AURKB mRNA levels, and thereby plays a role in cytokinesis and in the spindle checkpoint.
Entrez Gene ID
Human10713
Mouse28035
Rat297336
UniProt ID
HumanQ53GS9
MouseQ3TIX9
RatB2GV41
Alternative Names
USP39; ubiquitin specific peptidase 39; ubiquitin specific protease 39; U4/U6.U5 tri-snRNP-associated protein 2; CGI 21; SAD1; small nuclear ribonucleoprotein 65kDa (U4/U6.U5); snRNP assembly defective 1 homolog (S.cerevisiae); SNRNP65; SAD1 homolog; SnRNP assembly defective 1 homolog; inactive ubiquitin-specific peptidase 39; U4/U6.U5 tri-snRNP-associated 65 kDa protein; 65K; CGI-21; HSPC332; FLJ33136; MGC75069
Function
Plays a role in pre-mRNA splicing as a component of the U4/U6-U5 tri-snRNP, one of the building blocks of the precatalytic spliceosome (PubMed:11350945, PubMed:26912367).
Regulates AURKB mRNA levels, and thereby plays a role in cytokinesis and in the spindle checkpoint. Does not have ubiquitin-specific peptidase activity (PubMed:18728397).
Biological Process
Biological Process cell cycle Source:UniProtKB-KW
Biological Process cell division Source:UniProtKB-KW
Biological Process mRNA processing Source:ProtInc1 Publication
Biological Process mRNA splicing, via spliceosome Source:UniProtKB1 Publication
Biological Process protein deubiquitination Source:InterPro
Biological Process RNA splicing Source:ProtInc1 Publication
Biological Process spliceosomal complex assembly Source:UniProtKB1 Publication
Cellular Location
Nucleus
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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Rabbit Anti-USP39 Recombinant Antibody (CBXU-035) (CAT#: CBMAB-U0151-CQ)

Mouse Anti-USP39 Recombinant Antibody (3205C5a) (CAT#: CBMAB-U0060-CQ)

Mouse Anti-USP39 Recombinant Antibody (4G11) (CAT#: CBMAB-A9829-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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