VSTM1

This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2010]
Full Name
Vascular Cell Adhesion Molecule 1
Function
Isoform 2
Behaves as a cytokine, promoting IL17A secretion by CD4+ T-cells, and differentiation and activation of IL17 producing helper T-cells (TH17).
Isoform 1
Inhibitory immune receptor involved in the regulation of phagocytes.
Biological Process
Biological Process immune system process Source:UniProtKB-KW
Cellular Location
Isoform 1
Membrane
Isoform 2
Secreted
Topology
Extracellular: 17-135
Helical: 136-156
Cytoplasmic: 157-236
PTM
Isoform 2 is N-glycosylated.
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Anti-VSTM1 antibodies

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Mouse Anti-VSTM1 Recombinant Antibody (CBFYA-0276) (CBMAB-X0406-FY)

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Target: VSTM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYA-0276
Application*: F, FN, IP, WB
Datasheet SDS

Recombinant Mouse Anti-VSTM1 Antibody (CBHb325) (CBMAB-Hb973-LY)

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Target: VSTM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBHb325
Application*: FC, FuncS, IP, WB
Datasheet SDS

Mouse Anti-VSTM1 Recombinant Antibody (2E12) (CBMAB-A9899-LY)

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Target: VSTM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 2E12
Application*: WB, E
Datasheet SDS

Mouse Anti-VSTM1 Recombinant Antibody (CBXS-3814) (CBMAB-S1085-CQ)

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Target: VSTM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-3814
Application*: F, FN, IP
Datasheet SDS

Rabbit Anti-VSTM1 Recombinant Antibody (104) (CBMAB-V0080-YC)

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Target: VSTM1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 104
Application*: E
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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